Expanding Role for Transcatheter Aortic Valve Replacement: Successful Transfemoral Implantation of a Medtronic CoreValve for Severe Aortic Regurgitation

Transcatheter aortic valve replacement for native aortic valve regurgitation as a bridge to liver transplantation

“…The original concept of TAVR was to implant a balloon‐expandable or self‐expanding transcatheter heart valve into a calcified native aortic valve and annulus. The calcification was presumed essential to secure the stent frame in place . It follows that isolated severe native AR, with no significant valvular or annular calcium deposition, has been a relative contraindication to TAVR .…”

“Valve in valve” implantation of two self‐expandable transcatheter aortic valves in a patient with aortic root aneurysm and massive aortic regurgitation: “A new TAVI option”

“…Pure AR is a major challenge for TAVI mainly because the lack of a calcified annulus where to anchor the transcatheter valve bears a relevant risk of valve dislodgement. Literature reports several cases of self‐expandable CoreValve implantation in this setting for treating patients with no other therapeutic options: in fact, due to its versatile design, the CoreValve has allowed to address complex clinical situations with success in a relatively simple manner . Recently, a multicenter registry including 43 patients with native AR demonstrated both the technical feasibility and the drawbacks of this procedure that often requires the use of two percutaneous prostheses even in carefully selected patients .…”