2024
DOI: 10.1039/d3lc00622k
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Expanding CAR-T cell immunotherapy horizons through microfluidics

Hyelee Kim,
Suyeon Kim,
Hyunjung Lim
et al.

Abstract: This review outlines Chimeric antigen receptor (CAR)-T cell manufacturing, highlights challenges, and explores successful microfluidic approaches and related technologies to address them.

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Cited by 4 publications
(1 citation statement)
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“…Microdroplet technology is to realize microscale uniform droplets by controlling the fluid and to solve the difficulties in the traditional production process by controlling the reaction process in the droplets. Microdroplet technology has a wide range of applications in the fields of biomedicine, chemical synthesis, and material modification and provides a new direction for the preparation of composite explosives. Different droplet formation methods include coaxial droplet chips, , T-shaped droplet chips, , and cross-focused focused droplet chips. , Domestic and foreign teams have successfully applied microdroplet technology in the field of energy-containing materials. In 2018, Wu et al realized the integrated preparation of CL-20/TNT eutectic assembly and spherical coatings.…”
Section: Introductionmentioning
confidence: 99%
“…Microdroplet technology is to realize microscale uniform droplets by controlling the fluid and to solve the difficulties in the traditional production process by controlling the reaction process in the droplets. Microdroplet technology has a wide range of applications in the fields of biomedicine, chemical synthesis, and material modification and provides a new direction for the preparation of composite explosives. Different droplet formation methods include coaxial droplet chips, , T-shaped droplet chips, , and cross-focused focused droplet chips. , Domestic and foreign teams have successfully applied microdroplet technology in the field of energy-containing materials. In 2018, Wu et al realized the integrated preparation of CL-20/TNT eutectic assembly and spherical coatings.…”
Section: Introductionmentioning
confidence: 99%