Expanded theory for the resolving power of a linear ion mobility spectrometer

Spangler, Glenn E.

doi:10.1016/s1387-3806(02)00841-2

Cited by 42 publications

(41 citation statements)

References 46 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…An enhanced model of phenomena influencing signal shape from the IMS detectors was presented by Spangler [14]. According to that model, processes occurring in the last passage of the drift path, i.e., in the space between the aperture grid and the collector electrode, play a very important role.…”

Section: Introductionmentioning

confidence: 99%

Generation of current pulses in collector electrode of IMS detectors

Puton

Siodlowski

2010

International Journal of Mass Spectrometry

View full text Add to dashboard Cite

Section: Introductionmentioning

confidence: 99%

Generation of current pulses in collector electrode of IMS detectors

Puton

Siodlowski

2010

International Journal of Mass Spectrometry

View full text Add to dashboard Cite

“…where t d is the drift time of the ion divided by the temporal width-at-half-height (W 0.5 ) of the ion mobility peak [14,16].…”

Section: Introductionmentioning

confidence: 99%

An ion mobility spectrometer sensor system for subsurface use

Morgos

Geroy

Sevier

et al. 2009

Int. J. Ion Mobil. Spec.

View full text Add to dashboard Cite

An ion mobility spectrometer (IMS) probe system for real-time, subsurface soil-gas sampling applications is presented. The system includes an IMS and supporting electronics encased in a 51 mm diameter stainless steel probe housing. The IMS was challenged in the laboratory with 2,6-di-tert-butylpyridine (DtBP) and tetrachloroethylene (PCE) in zero air yielding reduced ion mobility constants (K o ) values of 1.42 cm 2 /Vs (n=3) and 1.79±0.01 cm 2 /Vs (n=3), respectively. A resolving power of 38 and 31 was obtained for DtBP and PCE, respectively. The system was deployed at a PCE-contaminated site to demonstrate its performance under field conditions. PCE was detected in the vapor samples as evidenced by peaks with a K o value of 1.80± 0.01 cm 2 /Vs for two measurements that were taken 6 min apart. The presence of PCE at the contaminated site was confirmed by GC-MS analysis of a gas sample at an EPAcertified laboratory, suggesting that this IMS system can be used to detect PCE under field conditions.

show abstract

“…Interactions between analyte ions and the drift gas result in a specific drift time for that ion, which is often converted to the reduced mobility (Formula 1) [1,2]. Several general reviews of IMS exist [1,[3][4][5][6][7][8] and the theory behind drift tube ion mobility spectrometry has been presented in detail elsewhere [2,9].where l d ϭ length of the drift region, t d ϭ drift time of ion, V ϭ voltage drop over the drift region, T ϭ temperature, and P ϭ pressure.The most common IMS devices are stand-alone instruments, which are commonly used to screen the environment for significant chemicals such as warfare agents, explosives, and illegal drugs [1, 10 -12]. These devices are often tuned to detect certain chemicals; when more specific information is required, IMS is often combined with other instruments, for example with gas chromatography (GC-IMS) [4,13].…”

mentioning

confidence: 99%

mentioning

confidence: 99%

Separation of different ion structures in atmospheric pressure photoionization-ion mobility spectrometry-mass spectrometry (APPI-IMS-MS)

Laakia

Adamov

Jussila

et al. 2010

J. Am. Soc. Mass Spectrom.

View full text Add to dashboard Cite

This study demonstrates how positive ion atmospheric pressure photoionization-ion mobility spectrometry-mass spectrometry (APPI-IMS-MS) can be used to produce different ionic forms of an analyte and how these can be separated. When hexane:toluene (9:1) is used as a solvent, 2,6-di-tert-butylpyridine (2,6-DtBPyr) and 2,6-di-tert-4-methylpyridine (2,6-DtB-4-MPyr) efficiently produce radical cations [M] ϩ· and protonated [M ϩ H] ϩ molecules, whereas, when the sample solvent is hexane, protonated molecules are mainly formed. Interestingly, radical cations drift slower in the drift tube than the protonated molecules. It was observed that an oxygen adduct ion, [M ϩ O 2 ] ϩ· , which was clearly seen in the mass spectra for hexane:toluene (9:1) solutions, shares the same mobility with radical cations, [M] ϩ· . Therefore, the observed mobility order is most likely explained by oxygen adduct formation, i.e., the radical cation forming a heavier adduct. For pyridine and 2-tert-butylpyridine, only protonated molecules could be efficiently formed in the conditions used. For 1-and 2-naphthol it was observed that in hexane the protonated molecule typically had a higher intensity than the radical cation, whereas in hexane:toluene (9:1) the radical cation [M] ϩ· typically had a higher intensity than the protonated molecule [M ϩ H] ϩ . Interestingly, the latter drifts slower than the radical cation [M] ϩ· , which is the opposite of the drift pattern seen for 2,6-DtBPyr and 2,6-DtB-4-MPyr. (J Am Soc Mass Spectrom 2010, 21, 1565-1572) © 2010 American Society for Mass Spectrometry I n ion mobility spectrometry (IMS) ions move through an applied electric field in a drift gas flow [1]. Interactions between analyte ions and the drift gas result in a specific drift time for that ion, which is often converted to the reduced mobility (Formula 1) [1,2]. Several general reviews of IMS exist [1,[3][4][5][6][7][8] and the theory behind drift tube ion mobility spectrometry has been presented in detail elsewhere [2,9].where l d ϭ length of the drift region, t d ϭ drift time of ion, V ϭ voltage drop over the drift region, T ϭ temperature, and P ϭ pressure.The most common IMS devices are stand-alone instruments, which are commonly used to screen the environment for significant chemicals such as warfare agents, explosives, and illegal drugs [1, 10 -12]. These devices are often tuned to detect certain chemicals; when more specific information is required, IMS is often combined with other instruments, for example with gas chromatography (GC-IMS) [4,13]. Ion mobility spectrometry-mass spectrometry (IMS-MS) is also becoming more and more popular in various application fields, especially in bioanalysis [5]. Several different types of ion mobility spectrometers have been combined with mass spectrometers, e.g., drift tube IMS-MS [1,5,14], field asymmetric ion mobility spectrometry (FAIMS-MS) [5,[15][16][17], and also an aspiration IMS method has been combined with MS [18]. In bioanalysis, a common application of IMS-MS is structural studies ...

show abstract

Expanded theory for the resolving power of a linear ion mobility spectrometer

Cited by 42 publications

References 46 publications

Generation of current pulses in collector electrode of IMS detectors

Generation of current pulses in collector electrode of IMS detectors

An ion mobility spectrometer sensor system for subsurface use

Separation of different ion structures in atmospheric pressure photoionization-ion mobility spectrometry-mass spectrometry (APPI-IMS-MS)

Contact Info

Product

Resources

About