1986
DOI: 10.1001/archinte.1986.00360170207027
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Expanded Role of Charcoal Therapy in the Poisoned and Overdosed Patient

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Cited by 58 publications
(22 citation statements)
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References 30 publications
(5 reference statements)
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“…Activated charcoal has been demonstrated to be effective in decreasing the area under the curve for absorbed aspirin, and it is the most widely used method of gastric decontamination for salicylate-poisoned patients [67,68]. Multidose activated charcoal similarly has been shown to reduce absorption of aspirin and results in decreased serum levels, but this has not translated into an improved morbidity or mortality rate [69].…”
Section: Gastric Decontaminationmentioning
confidence: 99%
“…Activated charcoal has been demonstrated to be effective in decreasing the area under the curve for absorbed aspirin, and it is the most widely used method of gastric decontamination for salicylate-poisoned patients [67,68]. Multidose activated charcoal similarly has been shown to reduce absorption of aspirin and results in decreased serum levels, but this has not translated into an improved morbidity or mortality rate [69].…”
Section: Gastric Decontaminationmentioning
confidence: 99%
“…Oral activated charcoal has been shown to enhance the elimination of other drugs from the body, including agents that do not undergo enterohepatic recycling, such as theophylline (1,2,4,7,9,12,13). The increase in drug clearance results from the adsorption of the drug onto the charcoal after diffusion into the gastrointestinal lumen from the circulation (10,14). This process would be even more effective in patients with toxic drug concentrations, since the diffusion gradient into the lumen would be greater.…”
Section: * Corresponding Authormentioning
confidence: 99%
“…Intoxication due to medications involve the use of medications for treatment, in addition to the more common high dose medication intake with suicidal intake (13,14). Suicidal attempt with high dose medication intake is the most common method of suicide (15).…”
Section: Discussionmentioning
confidence: 99%