1988
DOI: 10.1016/s0890-5096(06)60773-5
|View full text |Cite
|
Sign up to set email alerts
|

Expanded PTFE Prostheses as Arterial Substitutes in Humans: Late Pathological Findings in 73 Excised Grafts

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1
1

Citation Types

0
12
0

Year Published

1990
1990
2017
2017

Publication Types

Select...
9
1

Relationship

0
10

Authors

Journals

citations
Cited by 47 publications
(12 citation statements)
references
References 20 publications
0
12
0
Order By: Relevance
“…Thus, e-PTFE has the required mechanical properties and excellent chemical stability as a synthetic material. However, thrombogenic reactions can occur between the surface of e-PTFE and blood resulting in poor performance as a small diameter, synthetic arterial substitute [200]. Immobilization of anti-thrombogenic moieties onto the surface provides one means to alter the physical and biological properties of the surface and surface modification is, therefore, required to covalently attach these organic moieties to the surface.…”
Section: Poly(tetrafluoroethylene)mentioning
confidence: 99%
“…Thus, e-PTFE has the required mechanical properties and excellent chemical stability as a synthetic material. However, thrombogenic reactions can occur between the surface of e-PTFE and blood resulting in poor performance as a small diameter, synthetic arterial substitute [200]. Immobilization of anti-thrombogenic moieties onto the surface provides one means to alter the physical and biological properties of the surface and surface modification is, therefore, required to covalently attach these organic moieties to the surface.…”
Section: Poly(tetrafluoroethylene)mentioning
confidence: 99%
“…Our teams of scientists have been actively working closely with clinicians for several decades. The retrieval programs of vascular grafts and heart valves harvested at reoperation or autopsy were instrumental in contributing to the improvements of devices for open surgery [20][21][22]. Consequently, our teams became involved with cardiovascular devices for percutaneous surgery, initially stent-grafts.…”
Section: Descriptive Clinical Achievementsmentioning
confidence: 99%
“…Relevant materials applied to generate bypass grafts basically comprise autologous vessels, e.g., saphenous veins or polymers such as polyethylene terephthalate (Dacron) and polytetrafluoroethylene (PTFE), which have been in clinical use for decades. However, autologous vessel grafts are often not or no longer available due to concomitant diseases, prior harvest or incompatible caliber [84,87], and although subject of intense research for many years, alloplastic materials are prone to high incidences of thrombotic occlusion, infectious complications, and restenoses due to intimal hyperplasia [18,19,113].…”
Section: Introductionmentioning
confidence: 99%