Expanded home hemodialysis: case reports

Pérez-Alba, Alejandro; Reque, Javier; Vázquez-Gómez, Milagros; Pons-Prades, Ramón

doi:10.1007/s11255-020-02455-5

Cited by 7 publications

(4 citation statements)

References 12 publications

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“…However, this higher reduction ratio has not been clearly related to a reduction in long‐term serum levels 23 . Moreover, HDx also seems to maintain this superiority over HD in short‐daily HD performed at home 24 …”

Section: Efficacy Comparison Of Hdf Versus Hdxmentioning

confidence: 92%

“…23 Moreover, HDx also seems to maintain this superiority over HD in short-daily HD performed at home. 24 Nevertheless, there is a disparity in results when comparing the reduction ratios obtained with HDx with those of HDF. Some studies report better reduction ratios with MCO membranes than with HDF, 7,25 while others report noninferiority of HDx versus post-HDF, 9,[26][27][28][29] and others still report slightly lower removal.…”

Section: Efficacy Comparison Of Hdf Versus Hdxmentioning

confidence: 99%

“…Post‐dilution online hemodiafiltration (post‐HDF) has progressively evolved and can be considered a safe, fully consolidated treatment with multiple clinical advantages 10 . The ESHOL study reported longer survival in patients receiving post‐HDF, 11 and post hoc analysis of three randomized clinical trials with mortality as the primary endpoint showed an association between convective volume and survival 11–13 . In this regard, obtaining a replacement volume greater than 21 L per session has been recommended to achieve this survival benefit 14 …”

Section: Introductionmentioning

confidence: 99%

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Hemodiafiltration (HDF) versus expanded hemodialysis (HDx)

Maduell

Broseta

2022

Seminars in Dialysis

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Medium cutoff (MCO) membranes have resulted in a novel dialyzer class designed to improve membrane permeability and have been postulated as an alternative to online hemodiafiltration since MCO membranes may achieve similar solute clearances.These membranes have been incorporated into clinical practice, and the term expanded HD (HDx) has been proposed to differentiate from high-flux hemodialysis.Efficacy, safety, and quality of life comparison of HDF versus HDx have been reviewed in this article.

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Section: Efficacy Comparison Of Hdf Versus Hdxmentioning

confidence: 92%

Section: Efficacy Comparison Of Hdf Versus Hdxmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Hemodiafiltration (HDF) versus expanded hemodialysis (HDx)

Maduell

Broseta

2022

Seminars in Dialysis

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“…Los filtros de medio cut-off empleados habitualmente en la clínica no han demostrado pérdidas superiores en albúmina a la hemodiafiltración online con diferentes filtros de HD 96 . Debido a que la albúmina se eliminaría más rápidamente al principio de la sesión 97 , al implementar estos filtros en HD más frecuente, la pérdida de albúmina pudiera ser superior; no obstante parece no afectar a sus niveles séricos, al menos al incrementar a cinco sesiones a la semana, quedando la duda del incremento a seis sesiones a la semana 98 . Seis sesiones a la semana que en regímenes cortos diarios pudiera ser necesario para alcanzar un correcto balance hídrico.…”

Section: Pregunta De Investigación C: Supervivencia Técnica De La Hdd Al Implementar Los Modelos Ticunclassified

Desarrollo y optimización de programas de hemodiálisis domiciliaria basados en modelos TIC

Alba¹

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The research work carried out within this PhD aims to discuss the possibilities that the Information and Communication Technologies (ICT) bring to the development of Home Hemodialysis programs (HDD) optimizing their medical outcomes. After a first approach to the state of the art of kidney substitution treatments, and in particular of the HDD, and the description of the first application of ICT based solutions to a kidney treatment in the year 2017, starting date of this research work, a mobile application, called Dialapp, was developed with the cooperation of the Nephrology Department and the Computing Department of the Hospital General de Castellón (Spain).This application allowed the physician to prescribe the HD session while patients can transmit their HD sessions' parameters manually through the application. The application also allowed two-way communication between patients and the medical team involved in their treatment. After some initial problems of data privacy, the application was launched in May 2019. At that moment, the HDD service providers started to launch two other telemonitoring remote systems. The first system used a direct online connection between the home HD session in the patient's home and the server in the hospital.This system automatically uploaded data in the hospital management server and created a dump

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Medium cut-off dialyzer for middle molecular uremic toxins in AKI and chronic dialysis

Fiorentino,

La Fergola,

De Rosa

2023

J Nephrol

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Uremic toxins accumulate in patients affected by renal failure and can deposit in different organs, including the kidneys and heart. Given their physicochemical characteristics, uremic toxins can contribute to organ dysfunction due to several pathobiological actions at cellular and molecular levels. Several uremic compounds have been described in serum and plasma from patients with acute kidney injury (AKI) and kidney failure; they are usually classified based on their molecular size and protein-binding properties. In this scenario, new dialytic approaches have been proposed in the last few years with the aim of improving uremic toxin removal. Recent studies which focused on the use of medium cut-off membranes in patients on chronic hemodialysis have shown a discrete ability to remove β2-microglobulin and other middle molecules, such as kappa and lambda free light chains, complement factor D and α1-microglobulin. However, current evidence is mainly based on the impact on short-term outcomes and, consequently, longer observational studies are necessary to confirm the efficacy and safety of the medium cut-off dialyzer. Here we present the state-of-the-art on the clinical application of medium cut-off membranes in AKI and chronic dialysis patients. Graphical abstract

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Expanded home hemodialysis: case reports

Cited by 7 publications

References 12 publications

Hemodiafiltration (HDF) versus expanded hemodialysis (HDx)

Hemodiafiltration (HDF) versus expanded hemodialysis (HDx)

Desarrollo y optimización de programas de hemodiálisis domiciliaria basados en modelos TIC

Medium cut-off dialyzer for middle molecular uremic toxins in AKI and chronic dialysis

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