We discuss the multi-hadron systems containing a heavy hadron. We consider the heavy quark spin symmetry at leading order in the 1/m Q expansion with a heavy quark mass m Q . We discuss that there exist doublet/singlet states as degenerate/non-degenerate states in mass for any internal structure of the multi-hadron systems. As concrete examples, we adopt the heavy meson effective theory conserving the heavy quark spin, and apply it to the hadron moleculeP ( * )N composed of the heavy mesonP ( * ) = (Qq) spin 0(1) (a heavy antiquarkQ and a light quark q) and a nucleon N, which leads to the doublet state. We further show thatP ( * ) mesons are degenerate in mass in nuclear matter, and that the doublet state exists. Behind the mass degeneracy in the multihadron systems, a new structure called the spin-complex is proposed as a specific form of the brown muck. At next-to-leading order, we show that, in the heavy hadron mass formula, the terms conserving (breaking) the heavy quark spin symmetry are related to the interaction vertices of the chromoelectric (chromomagnetic) gluon and the heavy quark. By utilizing this property, we propose to use heavy hadrons as probes to investigate the modifications of the gluon fields in medium. Concretely, we perform the analysis of the in-medium masses ofP ( * ) meson in nuclear matter based on the heavy meson effective theory, and predict that the chromoelectric gluon is enhanced, while the chromomagnetic gluon is suppressed.