Exosomes from Hypoxia Preconditioned Muscle‐Derived Stem Cells Enhance Cell‐Free Corpus Cavernosa Angiogenesis and Reproductive Function Recovery
Tianwen Peng,
Muyuan Chai,
Zhicong Chen
et al.
Abstract:Tissue engineering for penile corpora cavernosa defects requires microvascular system reconstruction.GelMA hydrogels show promise for tissue regeneration. However, using stem cells faces challenges such as immune rejection, limited proliferation and differentiation, and biosafety concerns. Therefore, acellular tissue regeneration may avoid these issues. Exosomes are used from muscle‐derived stem cells (MDSCs) to modify 3D‐printed hydrogel scaffolds for acellular tissue regeneration. Hypoxia‐preconditioned MDSC… Show more
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