Exosomes from adipose‐derived stem cells regulate macrophage polarization and accelerate diabetic wound healing via the circ‐Rps5/miR‐124‐3p axis
Dongjing Yin,
Guoliang Shen
Abstract:BackgroundAdipose‐derived stem cells (ADSCs) hold promising application prospects in the treatment of diabetic wounds, although the underlying mechanisms of repair have not been fully elucidated. This research aimed to elucidate the mechanisms by which ADSCs promote wound healing.MethodsExosomes from ADSCs were isolated and circRps5 level was identified. To investigate the role of circRps5 in the regulation, exosomes from differently treated ADSCs were used. Different exosomes were injected into the edge of th… Show more
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