Exosomes: efficient macrophage-related immunomodulators in chronic lung diseases
Jianxiong Kang,
Peiyan Hua,
Xiaojing Wu
et al.
Abstract:Macrophages, the predominant immune cells in the lungs, play a pivotal role in maintaining the delicate balance of the pulmonary immune microenvironment. However, in chronic inflammatory lung diseases and lung cancer, macrophage phenotypes undergo distinct transitions, with M1-predominant macrophages promoting inflammatory damage and M2-predominant macrophages fostering cancer progression. Exosomes, as critical mediators of intercellular signaling and substance exchange, participate in pathological reshaping o… Show more
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