Exosomes derived from human placental mesenchymal stem cells in combination with hyperbaric oxygen synergically alleviates spinal cord ischemia-reperfusion injury

Mesenchymal stem cell-derived exosomes as a new drug carrier for the treatment of spinal cord injury: A review

“…Meanwhile, Jafari et al. 115 reported that exosomes from human placenta-derived MSCs worked synergistically with hyperbaric oxygen therapy to mitigate oxidative stress, apoptosis, and mitochondrial dysfunction in a spinal cord ischemia-reperfusion injury rat model. This indicates the antioxidant capacities of human placental MSC-Exo, likely due to placental MSCs residing in a hypoxic niche.…”