Exosome is an important novel way of acupuncture information transmission

Effects of acupoint herbal patching as an add-on to asthma medication during Sanfu days, as the hottest days in summer, on the acute attack, the immunological response, and the pulmonary function in asthmatic children: A meta-analysis

“…A total of 743 unique studies were identified, of which 13 randomized clinical studies (between 2003 and 2021) fulfilled the inclusion criteria and were included in this meta-analysis. [10–22] The 13 studies included 1166 asthmatic children at the start of the study; 587 of them were using acupoint herbal patching as an add-on to asthma medication during Sanfu days and 579 were given asthma medication only. All studies evaluated the effects of acupoint herbal patching as an add-on to asthma medication during Sanfu days compared to asthma medication only on the acute attack, the immunological response, and the pulmonary function in asthmatic children.…”

“…Eight studies [10,12,14,18–22] including 800 subjects reported data stratified to the effect on forced expiratory volume in 1 second, findings of this analysis as seen in Figure 4, showed a higher forced expiratory volume in 1 second (MD, 1.72; 95% CI, 0.89–2.65, P < .001) with high heterogeneity ( I 2 = 86%) in favor of interventional group receiving the add-on therapy compared with control (Fig. 4).…”

“…Seven studies [10,14,17–19,21,22] including 584 subjects reported data stratified to the effect on peak expiratory flow reflected higher peak expiratory flow rate (MD, 1.15; 95% CI, 0.37–1.93, P = .004) with high heterogeneity (I 2 = 88%) of interventional group compared with group receiving traditional asthma therapy only (Fig. 5).…”

“…Several randomized clinical trials have assessed the supplementary advantageous properties of acupoint herbal patching through the Sanfu days for treating asthma in children. [10–22] Though, the advantageous properties of acupoint herbal patching on the pulmonary functions are still conflicting. A previous meta-analysis showed that acupoint herbal patching had advantageous immunomodulatory properties for asthma in children.…”

Changes in Acupuncture‐Induced Specific Acupoint Neurotransmitters are Possibly Related to Their Physiological Functions in Rats

“…Taken together, purinergic receptors, sensory nerves, and mechanoreceptors play a crucial role in acupuncture signal transmission. In addition, acupuncture signal transmission includes circular and neural transmission [ 9 ]. To determine the specific physiological functions of acupoints for clinical application, the present study investigated changes in neurotransmitters released in muscle tissues surrounding the acupoints and in the extracellular fluid, peripheral blood, and cerebrospinal fluid (CSF) after the application of acupuncture at the Zusanli (ST36) and Neiguan (PC6).…”