Exon 8 amplification of epidermal growth factor receptor (<i>EGFR</i>) in invasive breast carcinomas

Souka, Efthimia; Alexiadis, Evaggelos; Theohari, Irini; Giannopoulou, Ioanna; Papadimitriou, Christos; Nakopoulou, Lydia

doi:10.1111/j.1365-2559.2012.04315.x

Histopathology

2012

DOI: 10.1111/j.1365-2559.2012.04315.x

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Exon 8 amplification of epidermal growth factor receptor (EGFR) in invasive breast carcinomas

Efthimia Souka¹,

Evaggelos Alexiadis²,

Irini Theohari³

et al.

Abstract: It appears that amplification of the coding sequence exon 8 exhibits similar biological behaviour to amplification of the regulatory sequence in intron 1, leading to elevated levels of EGFR protein.

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Exon 8 amplification of epidermal growth factor receptor (EGFR) in invasive breast carcinomas

Abstract: It appears that amplification of the coding sequence exon 8 exhibits similar biological behaviour to amplification of the regulatory sequence in intron 1, leading to elevated levels of EGFR protein.

Cited by 2 publications

References 37 publications

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