Exogenous Toxins and CNS Injuries

Bilateral lesions of the basal ganglia and thalami (central grey matter)—pictorial review

“…The signal abnormality may extend into the adjacent portions of the cerebellum, brainstem and insulae, along with a mild mass effect. Haemorrhagic lesions of bilateral globus pallidus or putamen, suggesting CO and methanol intoxication, have also been reported [77][78][79][80].…”

“…The accumulation of glycolic acid leads to metabolic acidosis and subsequent encephalopathy. The metabolic effects occur 12–24 h post-ingestion, comparable to methanol [ 77 , 78 ].…”

Determination of the Effect of Polyphenols on Certain Biochemical Changes (Alt, Ast, Alkaline Phosphotase and Total Protein) in the Conditions of Toxic Hepatitis

“…ALT activity is proportional to the amount of pyruvate dinitrophenylhydrazones formed in an alkaline medium and was determined by colorometric method (Table 1.2). The principle of spectrophotometric measurement of catalase activity is based on the ability of hydrogen peroxide to form a stable colored complex with molybdenum salts [3] The reaction was started by adding 0.1 ml of homogenate to 2 ml of 0.03% hydrogen peroxide solution. 0.1 ml of distilled water was added to the blank sample instead of serum.…”