Exogenous surfactant instillation in lung donors to reduce early graft dysfunction

Strueber, M.; Niedermeyer, J; Warnecke, G.; Gohrbandt, B.; Fischer, Stefan; Lindenberg, Barry S.; Simon, Andrè; Haverich, Axel; Hohlfeld, Jens M.

doi:10.1016/s1053-2498(02)00907-5

Search citation statements

Order By: Relevance

Paper Sections

Select...

Surfactant1

Discussion1

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2004

2007

Publication Types

Select...

Article3

Relationship

Self Cite0

Independent3

Authors

Journals

Cited by 3 publications

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Early results showed better lung function in the treated group as compared with the control group. 77 In conclusion, the experimental findings and early clinical experience indicate that exogenous surfactant therapy is a promising therapeutic intervention for patients with PGD. Prospective, randomized studies are needed to confirm these results.…”

Section: Surfactantmentioning

confidence: 88%

Report of the ISHLT Working Group on Primary Lung Graft Dysfunction Part VI: Treatment

Shargall

Guenther

Ahya

et al. 2005

The Journal of Heart and Lung Transplantation

115

View full text Add to dashboard Cite

Section: Surfactantmentioning

confidence: 88%

Report of the ISHLT Working Group on Primary Lung Graft Dysfunction Part VI: Treatment

Shargall

Guenther

Ahya

et al. 2005

The Journal of Heart and Lung Transplantation

115

View full text Add to dashboard Cite

“…11 Struber recently reported that donor pre-treatment with 100 mg/kg of bovine surfactant prior to organ retrieval resulted in improved lung function when compared with a control group. 16 A considerable number of donor lungs are considered unsuitable for transplantation because of poor gas exchange in the absence of aspiration, infection or pulmonary contusion. Exogenous surfactant administration may expand the marginal donor pool, although further trials are required.…”

Section: Discussionmentioning

confidence: 99%

Resolution of Severe Ischemia–Reperfusion Injury Post–Lung Transplantation After Administration of Endobronchial Surfactant

Kermeen

McNeil

Fraser

et al. 2007

The Journal of Heart and Lung Transplantation

View full text Add to dashboard Cite

Lung preservation

Perrot

Keshavjee

2004

Seminars in Thoracic and Cardiovascular Surgery

View full text Add to dashboard Cite

Better understanding of the mechanisms of ischemia-reperfusion injury, improvement in the technique of lung preservation, and the recent introduction of a new preservation solution specifically developed for the lungs have helped to reduce the incidence of primary graft dysfunction after lung transplantation. Currently, the limitation in extending the ischemic time is more often related to the increasing use of non-ideal lung donors rather than to poor lung preservation. In this review, we have focused our attention on the experimental and clinical work performed to optimize the methods of lung preservation from the time of retrieval to the period of reperfusion after graft implantation.

show abstract

Exogenous surfactant instillation in lung donors to reduce early graft dysfunction

Cited by 3 publications

References 0 publications

Report of the ISHLT Working Group on Primary Lung Graft Dysfunction Part VI: Treatment

Report of the ISHLT Working Group on Primary Lung Graft Dysfunction Part VI: Treatment

Resolution of Severe Ischemia–Reperfusion Injury Post–Lung Transplantation After Administration of Endobronchial Surfactant

Lung preservation

Contact Info

Product

Resources

About