Exogenous Lipoid Pneumonia: Dramatic Clinical and Radiological Improvement After Multiple Segmental Bronchoalveolar Lavages

Modaresi, Mohammadreza; Dadkhah, Minoo; Sayedi, Seyed Javad

doi:10.5812/ijp.3172

Cited by 6 publications

(5 citation statements)

References 5 publications

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“…Although it is radiologically indistinguishable from various pathologies with alveolar occupation and ground-glass such as bacterial pneumonia; a common denominator in thorax x -rays are the diffuse ground-glass appearance with alveolar interstitial opacities, presence of air bronchogram with consolidation, nodular lesions, reticular and alveolar interstitial pattern, which are the most common findings in the thoracic x-ray and CAT [6,8,20]. The lower lobes and the right middle lobe are commonly involved, but multifocal and bilateral lesions can also be observed [21][22][23], as well as bad-defined nodules, pneumatoceles, and pleural effusion [24]. The treatment is based on multiple bronchoalveolar lavages that can eliminate lipid-loaded macrophages as the main cause of fibrosis in the alveoli and the interstitium [9,25], which, in the present clinical case, had to be differed due to the ventilatory and hemodynamic instability.…”

Section: Discussionmentioning

confidence: 99%

Radiological Manifestations of Serious Exogenous Lipoid Pneumonia. Case Report

Vergara¹

2020

BJSTR

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Exogenous lipoid pneumonia is an uncommon disease that occurs by the accidental ingestion of lipid material. The radiological manifestations tend to be heterogeneous and must correlate with the amount and characteristics of the aspirated material. The diagnosis is established by histopathology. Clinical Case:We report the radiological characteristics of an infant female patient of one year of age with severe exogenous lipoid pneumonia secondary to oil aspiration. Conclusions:The radiological manifestations include ground-glass pattern, consolidation regions with air bronchogram predominantly toward the bases, and posterior segments. The thoracic x-ray and CT scan may fundament the suspected diagnosis in some pediatric centers that do not have a bronchoscopy and can be a prognostic factor in seriously ill patients.

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Section: Discussionmentioning

confidence: 99%

Radiological Manifestations of Serious Exogenous Lipoid Pneumonia. Case Report

Vergara¹

2020

BJSTR

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“…Antibiotic treatment for severe cases seems justified, considering bacterial superinfection [[7], [8], [9], [10], [11], [12], [13]]. Several case reports demonstrated the effectiveness of therapeutic lung lavage for lipoid pneumonia, which not only washed away lipids directly but also improved lung opacities [[15], [16], [17]]. Steroids are suggested for the treatment of lipoid pneumonia and have been proved successful in some cases, however, the efficiency of steroids mostly depending on the degree of intoxication [[5], [6], [7], [8], [9], [10],18,[22], [23], [24]].…”

Section: Discussionmentioning

confidence: 99%

“…89 case reports were found. Upon the review of titles, abstracts, and full texts of these publications, we identified 22 articles (25 cases) describing exogenous lipid pneumonia caused by aspiration [[3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24]]. In particular, we found 3 articles describing 2 cases among these articles [17,20,24].…”

Section: Literature Reviewmentioning

confidence: 99%

Exogenous lipid pneumonia in old people caused by aspiration: Two case reports and literature review

Guo

Liu

Jiang

2019

Respiratory Medicine Case Reports

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Background Exogenous lipoid pneumonia is a rare entity, the diagnosis is often missed or delayed. Objective To investigate the clinical characteristics of exogenous lipid pneumonia in elderly patients, improve the efficiency of early diagnosis and treatment of this disease. Methods Retrospectively analyzed the clinical information and imaging data of these 2 exogenous lipid pneumonia patients, reviewed related literature. Results Both of the 2 patients were over 60 with a history of gastrointestinal diseases. The clinical presentation is nonspecific. Chest CT showed many different manifestations. Histopathology analysis revealed the accumulation of lipid carrying macrophages, vacuolar cells and inflammation. A literature review indicated that 25 previous cases of exogenous lipid pneumonia were caused by aspiration. The most common site of the lesion was located in right lung, while mineral oil was the most common substances. We sought to discuss the patient's treatment and the corresponding outcomes. Conclusion The diagnosis of lipid pneumonia's mainly depends on medical history and histopathological morphology. The standard treatment for exogenous lipid pneumonia was composed of antibiotics, steroid, bronchoscopic lavage and a regular follow-up.

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“…Steroids alone or in combination with intravenous immunoglobulin and large volume or segmental lung lavage have been used with reasonable success. 8,9…”

Section: Discussionmentioning

confidence: 99%

Acute exogenous lipoid pneumonia presenting as spontaneous air leak following accidental baby oil aspiration

et al. 2019

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Exogenous lipoid pneumonia (ELP) is an uncommon cause of respiratory distress. The practice of oil massage and oil instillation into the nostrils is common in the Indian subcontinent. Accidental aspiration of baby oil may lead to significant chemical pneumonitis. This presentation may vary from subtle to severe respiratory distress requiring intensive care management. Spontaneous air leaks are rare in acute ELP. We successfully managed a six-month-old girl presenting with mineral oil-induced ELP and air leaks. However, these children require long-term follow-up, as a small proportion may evolve into chronic lung disease.

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Exogenous Lipoid Pneumonia: Dramatic Clinical and Radiological Improvement After Multiple Segmental Bronchoalveolar Lavages

Cited by 6 publications

References 5 publications

Radiological Manifestations of Serious Exogenous Lipoid Pneumonia. Case Report

Radiological Manifestations of Serious Exogenous Lipoid Pneumonia. Case Report

Exogenous lipid pneumonia in old people caused by aspiration: Two case reports and literature review

Acute exogenous lipoid pneumonia presenting as spontaneous air leak following accidental baby oil aspiration

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