Exogenous Epigallocatechin-3-Gallate Alleviates Pesticide Phytotoxicity and Reduces Pesticide Residues by Stimulating Antioxidant Defense and Detoxification Pathways in Melon

Wu, Yaxian; Ahammed, Golam Jalal; Li, Zhengzhen; Wang, Yameng; Wang, Qianying; Fang, Mingya; Zhang, Yanping; Liu, Haihe; Li, Xin

doi:10.1007/s00344-023-11092-y

Cited by 3 publications

(3 citation statements)

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“…4). An increase in secondary metabolites levels may stimulate the detoxi cation process of H 2 O 2 and thus could protect cell from lipid peroxidation (Wu et al 2023). Similar to our studies, Mohamed and Akladious (2017) reported that the avonoid content increased in cotton plants treated with Flosan, Hemixet, and Maxim fungicides.…”

Section: Discussionsupporting

confidence: 89%

“…Consistent with the results of previous research, the glutathione detoxi cation pathway "green-liver" actively participated in the chlorothalonil detoxi cation process in tomato seedlings (Shan et al 2022). Interestingly, our results indicated that DIF and NaCl co-contamination may increase GST activity more than both pollutants single exposure, so that more GST is involved in the detoxi cation of combined contamination (Touzout 2023;Wu et al 2023). Besides GST, Peroxidase (POD) plays an important role in xenobiotic detoxi cation and is regarded as a biomarker of phytotoxicity (Liu and Wu 2018).…”

Section: Discussionmentioning

confidence: 83%

“…Accumulation of pesticides in plant tissues alters the physiological and biochemical processes, disrupts metabolism and hinders plant growth (Sharma et al 2018;Mahapatra et al 2019). For example, Wu et al (2023) reported that pesticide (glyphosate and carbendazim) treatment inhibits photosynthesis, plant growth and cause the accumulation of pesticide residues in melon (Cucumis melo) plants, which poses a serious threat to human health via the food chain. Difenoconazole fungicide caused phytotoxicity and DNA alterations (cytotoxicity, genotoxicity, and mutagenicity) in Allium cepa (Bernardes et al 2015).…”

Section: Introductionmentioning

confidence: 99%

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Breaking New Ground: Uncovering the Synergistic Impact of Difenoconazole and Salt on Tomato (Solanum lycopersicum L) Growth, Photosynthetic Pigments, and Oxidative Stress

Touzout,

Hassani,

Bouzidi

et al. 2023

Preprint

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Studies have shown that exposure to either fungicide difenoconazole (DIF) or salt (NaCl) alone can cause phytotoxicity in plants, but it remains uncertain whether co-exposure to these two xenobiotics, which often co-occur in the agroecosystem, can also induce phytotoxicity. This research aimed to study the phytotoxicity and underlying mechanisms of co-exposure to DIF (field recommended doses (0.5 L ha− 1) and NaCl (150 mM) in tomato seedlings. The results showed that exposure to DIF and/or NaCl causes phytotoxic effects in tomato seedlings, including a decrease in fresh weight and length of shoots and roots, damage to chlorophyll pigment, and induced oxidative stress in the leaves. Interestingly, combined exposure to DIF and NaCl exhibited synergistic effects on shoot and root biomass inhibition. Antioxidant defense analyses revealed that the DIF and/or NaCl exposure altered the activities of enzymes involved in the H2O2 scavenging (ascorbate peroxidase and catalase), and in xenobiotic detoxification (glutathione-s-transferase and peroxidase) in leaf tissues. Interestingly, combined exposure to DIF and NaCl markedly enhanced detoxifying enzymes, thereby enhancing xenobiotic biotransformation. In addition, DIF and/or NaCl exposure enhanced proline accumulation, and altered the thiols profile (reduced glutathione) content, while stimulating the phenylpropanoid pathway (phenylalanine ammonia-lyase activity) to produce secondary metabolites such as polyphenols and flavonoids. As pioneer research to highlight the phytotoxicity induced by co-exposure to DIF and NaCl in tomato seedlings, these results provide new insights into physio-biochemical responses of non-target plants to DIF and NaCl co-contamination and shedding light on the ecological risks of pesticides and salt exposure in agroecosystems.

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Section: Discussionsupporting

confidence: 89%