Exocrine pancreatic changes following acute attack of biliary pancreatitis

Endocrine pancreatic insufficiency in chronic pancreatitis

“…Pareja et al [25] examined prospectively the exocrine function of 63 cholecystectomized patients with acute biliary pancreatitis and reported no observable functional change a year later, regardless of the severity of the attack. Changes in hydrocarbonate metabolism described in AP are characterized by the presence of hyperglycemia and changes in insulin and glucagon secretion in up to 50% of the cases [26,27] after an acute episode.…”

Acute biliary pancreatitis: Does the pancreas change morphologically in the long term?

“…In our series, we observed no acinar fi lling in either patients or control group, which suggests that the fi ndings observed after MRCP can be sequelae or AP scarring, and do not indicate evolution towards a chronic condition. This is supported by the fact that all the patients showed normal exocrine and endocrine functional reserve and no patients showed defi cit in their pancreatic function [12,13] .…”

“…A prospective study of the exocrine and endocrine pancreatic function was made on 48 patients from among those who were admitted consecutively to the Department of General and Digestive Surgery of the Valencia University General Hospital from July, 1994 to December, 1995 [12,13] . These 48 patients were diagnosed as having ABP, according to the criteria of our work group [12,13] .…”

“…These 48 patients were diagnosed as having ABP, according to the criteria of our work group [12,13] .…”

“…The functional pancreatic study included exocrine and endocrine function assessment [12,13] . The pancreatic morphology study included: a dynamic contrast enhanced CT at 1 month after ABP, which was repeated at 6 and 12 months after ABP only when the results of the previous CT had been abnormal, and the MRCP at fi ve years from the episode of pancreatitis, analyzing the morphology of the pancreatic gland and also the condition of the MPD.…”