Existence of renal dysfunction in diabetics undergoing coronary artery bypass

Naeem, Syed; Ali, Taimur Asif; Fatimi, Saulat Hasnain

doi:10.1177/0218492316658375

Cited by 2 publications

(2 citation statements)

References 14 publications

(38 reference statements)

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“…Indeed, renal function is included in the STS and EuroSCORE risk scores for predicting CABG outcomes 2,3 . There is a graded increase in operative mortality and morbidity with worsening preoperative renal function 1,4–11 . Renal insufficiency is associated with a greater risk of both 30‐day and 1‐year mortality 12 .…”

Section: Introductionmentioning

confidence: 99%

“…2,3 There is a graded increase in operative mortality and morbidity with worsening preoperative renal function. 1,[4][5][6][7][8][9][10][11] Renal insufficiency is associated with a greater risk of both 30-day and 1-year mortality. 12 Even mild renal dysfunction is associated with increased rates of operative and long-term mortality, need for postoperative dialysis, and postoperative stroke.…”

Section: Introductionmentioning

confidence: 99%

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The predictive value of five glomerular filtration rate formulas for long‐term mortality in patients undergoing coronary artery bypass grafting

Ram

Peled

Karni

et al. 2022

Journal of Cardiac Surgery

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Background and Aims: Renal function plays an important role in the management of patients referred for coronary artery bypass grafting (CABG). Current data is insufficient for precise risk stratification using the estimated glomerular filtration rate (eGFR). Methods: This retrospective study includes 3744 consecutive patients who underwent CABG between 2004 and 2020. We assessed five different eGFR formulas: Cockcroft-Gault (CG), modification of diet in renal disease (MDRD), chronic kidney disease Epidemiology Collaboration (CKD-EPI), Mayo, and inulin clearance-based (IB).Results: The Mayo formula yielded the highest mean eGFR (90 ± 24 ml/min per 1.73 m 2 ) and CKD-EPI the lowest (74 ± 21 ml/min per 1.73 m 2 ). As a result, more patients were classified as having a normal renal function (57%) with the Mayo formula as compared with the others. Using MDRD as the reference formula, there was a significant and stronger correlation between the values obtained from the CKD-EPI (r = .95, p < .001) and Mayo (Mayo: r = .87, p < .001) compared to the IB (r = .8, p < .001) and CG (r = .79, p < .001) formulas. Multivariable analysis demonstrated that decreased renal function is an independent predictor of 10-year mortality in all five formulas, with risk increasing by 13-17% for each 10-unit decrease in eGFR. Despite the similarities between the formulas, the ability to predict mortality was highest in the Mayo formula and lowest in the CG and IB.Conclusions: Our data suggest that the Mayo formula may be superior to the other formulas in prognosticating mortality after CABG. We have shown that the Mayo equation classified fewer individuals as having renal dysfunction and more accurately categorized the risk for mortality than did all other formulas.

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Section: Introductionmentioning

confidence: 99%