Existence of Hepatitis B Surface Protein Mutations and Other Variants:  Demand for Hepatitis B Infection Control in Cambodia

Abstract

AimsThis study aimed to detect Hepatitis B virus (HBV) genome sequences and their variants as of nationwide scale using dried blood spot (DBS) samples and to provide up-to-date reference data for infection control and surveillance in Cambodia. MethodAmong 2,518 children age 5-7 years and their 2,023 mothers participated in 2017 Cambodia nationwide sero-survey on hepatitis B surface antigen (HBsAg) prevalence using multistage random