Exfoliation syndrome in enucleated haemorrhagic and absolute glaucoma

Abstract

Occurrence of exfoliation syndrome was studied in 172 eyes enucleated for haemorrhagic and absolute glaucoma in 1962-82, using histopathological techniques. Exfoliation was found in 33% of haemorrhagic glaucoma cases and in 22% of absolute glaucoma. In patients over 70, exfoliation was found in 53% of the haemorrhagic cases and in 46% of the absolute glaucoma cases. Capsular glaucoma may provoke haemorrhagic glaucoma and may lead to blindness and enucleation of eye with or without vascular catastrophe.

Association of exfoliation syndrome and central retinal vein occlusion: an ultrastructural analysis

“…Based on our results and previous studies, we believe that patients with CRVO should be investigated carefully for XFS, especially when considering the management of the fellow eye. Saatci et al (1999) Slit-lamp biomicroscopy 53 20.8% (95% CI 12-34%) Cursiefen et al (1997) Chart review 159 6.9% (95% CI 4-12%) Karjalainen et al (1987) Histopathological 55 40% (95% CI 28-53%) Present study Slit-lamp biomicroscopy, conjunctival biopsy 36 61.1% (95% CI 45-75%) CI, confidence interval.…”

“…An increased association has also been found in histopathological studies. In one series, approximately 33% of all eyes enucleated for neovascular glaucoma caused by CRVO had coexistent XFS (Karjalainen et al. 1987).…”

“…An increased association has also been found in histopathological studies. In one series, approximately 33% of all eyes enucleated for neovascular glaucoma caused by CRVO had coexistent XFS (Karjalainen et al 1987). Cursiefen et al (2001) found XFM in 10% of eyes enucleated for secondary angle-closure glaucoma and rubeosis iridis secondary to CRVO and examined by light microscopy.…”

“…Central retinal vein occlusion (CRVO) has been associated with XFS at variable frequencies based upon retrospective studies that employed either slit‐lamp examination or histopathology, but no electron microscopic analysis of extraocular tissues (Meyer et al. 1984; Pohjanpelto 1985; Karjalainen et al. 1987; Cursiefen et al.…”

“…Acute retinal vascular occlusions are blinding disorders, and yet there is marked controversy on their pathogeneses and clinical features (David et al 1988;Hayreh 2005). Central retinal vein occlusion (CRVO) has been associated with XFS at variable frequencies based upon retrospective studies that employed either slit-lamp examination or histopathology, but no electron microscopic analysis of extraocular tissues (Meyer et al 1984;Pohjanpelto 1985;Karjalainen et al 1987;Cursiefen et al 1997Cursiefen et al , 2001Saatci et al 1999;Gillies & Brooks 2002).…”