Exergaming in the treatment of gait, balance, and quality of life in Parkinson's disease: Overview of systematic reviews

Abstract

Introduction:Postural instability and gait impairments are common in people with PD, both of which have a negative effect on their quality of life. Systematic reviews have demonstrated benefits of using exergaming in enhancing these outcomes.However, there is no consensus over whether exergaming therapy is better than conventional physical therapy for enhancing gait, balance, and quality of life. Objectives: The aim of this overview is to systematically synthesize and evaluate the available evidence found in published systematic reviews and meta-analyses, on the effects of exergaming therapy on balance, gait, and quality of life, compared to conventional physical therapy or no intervention.Methods: This overview was reported in accordance with the statement of Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA). A comprehensive search was carried out in nine databases. Two reviewers independently extracted data using a standardized forms and the search strategy included terms related to intervention, population, and study type. The methodological quality of the included systematic reviews/meta-analysis (SRs/Mas) was evaluated using the "A Measurement Tool to Assess Systematic Reviews 2" (AMSTAR-2). The "Grading of Recommendations Assessment, Development and Evaluation" (GRADE) was used to assess the quality of the evidence. The risk of bias assessment was performed using the "Risk Of Bias In Systematic Reviews" (ROBIS). PROSPERO registration number: CRD42021238131.Results: 112 SRs/MAs were found and nine of them were selected. Six reviews were rated as very low methodological quality and three reviews as low methodological quality. Five reviews were classified with low risk of bias and four reviews with high risk of bias. Most of the SR/MAs demonstrated significant effects on balance favoring exergaming therapy over conventional therapy, however those studies had been rated as very low quality of evidence. Inconclusive results were found for the quality of life and gait outcomes. Conclusion:Exergaming therapy shows promise for the rehabilitation of PD. However, this overview was unable to conclude with certainty that exergaming therapy is superior to conventional physical therapy in improving gait, balance, or

Effectiveness of Neurorehabilitation in Improving the Functional Recovery and Quality of Life of Patients With Parkinson's Disease: A Case Report

“…showed that there is potential for PD rehabilitation with exercise gaming treatment [15]. A study by Maranesi et al concluded that with its integration of cognitive and physical activities inside a virtual, enhanced, or interactive gaming environment, exergaming-based technological rehabilitation might be more innovative than the traditional approach [16].…”

Research hotspots and trends of transcranial magnetic stimulation in Parkinson’s disease: a bibliometric analysis

“…Based on the results of keyword burst and cluster analysis motor function in people with PD has received increasing attention from researchers in the past decades. This reason can be the freezing of gait is one of the common motor symptoms in patients with PD and is a major risk factor for falls, which greatly reduces mobility and quality of life ( Giladi and Nieuwboer, 2008 ; Nutt et al, 2011 ; Rocha et al, 2023 ). Recent studies suggested that TMS has a certain improvement effect on some indicators of gait in people with PD, and this effect is not maintained in the long term, but only in the short term ( Xie et al, 2020 ).…”