Virtual reality is three dimensional, interactive and fun way in rehabilitation. Its irst known use in rehabilitation published by Max North named as "Virtual Environments and Psychological Disorders" (1994). Virtual reality uses special programmed computers, visual devices and artiicial environments for the clients' rehabilitation. Throughout technological improvements, virtual reality devices changed from therapeutic gloves to augmented reality environments. Virtual reality was being used in diferent rehabilitation professions such as occupational therapy, physical therapy, psychology and so on. In spite of common virtual reality approach of diferent professions, each profession aims diferent outcomes in rehabilitation. Virtual reality in occupational therapy generally focuses on hand and upper extremity functioning, cognitive rehabilitation, mental disorders, etc. Positive efects of virtual reality were mentioned in diferent studies, which are higher motivation than non-simulated environments, active participation of the participants, supporting motor learning, fun environment and risk-free environment. Additionally, virtual reality was told to be used as assessment. This chapter will focus on usage of virtual reality in occupational therapy, history and recent developments, types of virtual reality technologic equipment, pros and cons, usage for pediatric, adult and geriatric people and recent research and articles.