Abstract:Background: Physical exercise is believed to play a vital role in the prevention and treatment of cancer and its complications. However, the molecular mechanisms underlying this effect remain unclear.
Methods: BALB/c female mice (n=24) were randomly divided into sedentary group (SED), exercise group (Ex), Doxorubicin group (Dox, 5 mg/kg), and Doxorubicin + exercise group (Dox + Ex) after 7 days of 4T1 cell implantation. Exercise training lasted for 28 days and included rotarod experiments and resistance train… Show more
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