Exercise training improves microvascular function in patients with Chagas heart disease: Data from the PEACH study

Borges, Juliana Pereira; Mendes, Fernanda de Souza Nogueira Sardinha; Rangel, Marcus Vinicius Dos Santos; Lopes, Gabriella de Oliveira; Silva, Gilberto Marcelo Sperandio da; Silva, Paula Simplício da; Mazzoli‐Rocha, Flavia; Saraiva, Roberto Magalhães; Sousa, Andréa Silvestre de; Tibiriçá, Eduardo; Mediano, Mauro Felippe Felix

doi:10.1016/j.mvr.2020.104106

Cited by 11 publications

(7 citation statements)

References 15 publications

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“…Hypertension and arteriosclerosis can lead to an increase in pressure and flow velocity within the blood vessels, causing significant shear forces on the vessel wall, causing damage to the vascular intima, and also leading to vascular remodeling, including thickening of the intima, middle layer, and outer membrane, leading to increased stiffness and resistance of the vessel wall, and poor blood flow. [ 32 ] Hypertension and arteriosclerosis can make coagulation factors and platelets in the blood more prone to aggregation, leading to thrombosis and changes in brain structure, such as cerebral aneurysms and microaneurysms, which may increase the risk of stroke. [ 33 ] Appropriate PA can improve the symptoms of arteriosclerosis in the middle-aged and elderly, restore the arteries of the elderly to normal function, and then reduce the risk of stroke in the middle-aged and elderly.…”

Section: Discussionmentioning

confidence: 99%

The relationship between physical activity and stroke in middle-aged and elderly people after controlling demography variables, health status and lifestyle variables

Zhang,

Jiang

2023

Medicine

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The increase in the number of stroke patients in China brain has led to the decline in quality of life and the burden of family economic conditions. This study explored the relationship between stroke and physical activity (PA) in middle-aged and elderly Chinese after controlling Demography, health status and lifestyle variables, providing a new basis for the prevention and treatment of stroke in the elderly. The data is from the 2018 China Health and Retirement Longitudinal study. Five thousand seventy people over 50 years old with complete information on PA, stroke, Demography, health status and lifestyle were included in the analysis. SPSS 27.0 software was used to conduct Z test, logistic regression analysis and linear hierarchical regression analysis on the collected data. The results showed that high-level physical exercise was significantly negatively correlated with stroke (P < .05). After adjusting Demographics characteristics (gender, registered residence type, education level, age, widowhood or not), health status characteristics and living habits (arthritis, bad mood, asthma, hyperlipidemia, disability, memory disease, health self-evaluation, hypertension, smoking, depression), There was still statistical significance (P < .05) between PA and stroke. This study concludes that middle-aged and elderly people with high PA have a lower risk of stroke. In the process of preventing and improving stroke symptoms in the elderly, it is important to maintain high PA while also paying attention to health management and a healthy lifestyle.

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Section: Discussionmentioning

confidence: 99%

The relationship between physical activity and stroke in middle-aged and elderly people after controlling demography variables, health status and lifestyle variables

Zhang,

Jiang

2023

Medicine

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“…[ 29 ] Physical exercise increases the myocardial thickness, promotes the improvement of cardiac function, and improves the inner diameter and elasticity of coronary arteries, thereby improving the cardiac function of the body and reducing the risk of hypertension in the body. [ 30 ] The above studies have found that hypertension and impaired endothelial vasodilation, arteriosclerosis, dysfunction of the sympathetic nervous system and renin-angiotensin-aldosterone system, abnormal glucose metabolism, dysfunction of pancreatic islets, and structural damage of left ventricle are all one of the risk factors for hypertension. Physical exercise can have a positive effect on these risk factors for hypertension, which will provide an important reference for the treatment of hypertension caused by different causes.…”

Section: Discussionmentioning

confidence: 99%

The relationship between hypertension and physical activity in middle-aged and older adults controlling for demographic, chronic disease, and mental health variables

Tian

Zhang

2022

Medicine

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To explore the relationship between hypertension and physical activity (PA) in the middle-aged and elderly after controlling demographic characteristics, chronic diseases and mental health variables. The 2018 China Health and Retirement Longitudinal Study (CHARLS) was used to collect the data. A baseline survey of middle-aged and older people was carried out nationally using the PPS sample method to look into their demographic, health state, and other information. The investigation included 4593 adults over 50 with complete data on PA level and hypertension prevalence. Z-test, logistic regression analysis, and linear hierarchical regression analysis were performed on the gathered data using the SPSS 27.0 program. The prevalence of hypertension among middle-aged and senior persons was 12.2%, and the percentage of those who did not have it was 87.8%. Males were more likely than females to have hypertension. Participants who reported high levels of PA made up 49.2% of the total, while those who reported low levels of PA made up 50.8% of the total. High levels of PA were significantly inversely correlated with hypertension (P < .05). There was still a statistically significant relationship between PA and hypertension (P < .05) after controlling demographic factors (gender, age, household registration type, education level, widowhood), chronic disease (arthritis, diabetes, disability, asthma, self-assessment of health, memory disease, stroke, hyperlipidemia) and mental health variables (bad mood and depression). High-level PA is significantly related to the low risk of hypertension. After controlling demographic characteristics, chronic diseases and mental health variables, this correlation is still significant.Abbreviations: BMI = body mass index, CHARLS = China health and retirement longitudinal study, CI = confidence interval, MET = metabolic equivalent of energy, OR = odds ratio, PA = physical activity, RCT = randomized controlled trial, RRAS = reninangiotensin-aldosterone system.

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“…42 Another study correlated physical training with improvement of microvascular function in these patients. 43 Despite their benefits, rehabilitation clinics are not widely available. Remote monitoring (telehealth) has been a support strategy to increase the access to specialized professionals.…”

Section: Non-pharmacological Treatmentmentioning

confidence: 99%

Advances in Clinical Practice, Diagnosis and Treatment of Chronic Chagas’ Heart Disease

Alves¹,

Silva²,

Barbosa³

et al. 2023

ABC Heart Fail Cardiomyop

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Chagas disease has become globalized as a result of the migratory process of infected patients to non-endemic areas. With the considerable number of individuals affected by the disease, detection and treatment of its chronic manifestations is a relevant and necessary issue. Growing attention has been paid to chronic Chagas cardiomyopathy (CCC), which includes heart failure, malignant arrhythmias, conduction disturbances and thromboembolic events. Many pharmacological and nonpharmacological treatments for CCC are still extrapolations of existing evidence on the treatment of other clinical conditions, highlighting the need of including this group of patients in future studies. In this review, we will discuss the most recent data from the literature and clinical practice on the diagnosis and treatment of CCC. IntrodutionChagas disease (CD) is a neglected tropical disease that affects socially vulnerable individuals that experience stigma, discrimination and high morbidity and mortality, especially those with the cardiac form of the disease. 1,2 Changes in the epidemiological landscape of CD have been described worldwide.With the migratory phenomenon, CD has become globalized. Especially coming from the Latin America, CD

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Exercise training improves microvascular function in patients with Chagas heart disease: Data from the PEACH study

Cited by 11 publications

References 15 publications

The relationship between physical activity and stroke in middle-aged and elderly people after controlling demography variables, health status and lifestyle variables

The relationship between physical activity and stroke in middle-aged and elderly people after controlling demography variables, health status and lifestyle variables

The relationship between hypertension and physical activity in middle-aged and older adults controlling for demographic, chronic disease, and mental health variables

Advances in Clinical Practice, Diagnosis and Treatment of Chronic Chagas’ Heart Disease

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