“…18 These recruiting challenges may also result in reduced generalizability of the study sample. Oldervall et al 70 found that consenters had higher education, a concern as those of lower socioeconomic status tend to do worse on most health indicators. As noted above, several studies only analyzed those who remained in the study at follow-up or who adhered to the intervention.…”
Section: Discussionmentioning
confidence: 99%
“…A 20-week aerobic intervention of thrice weekly activity for 30-40 min after treatment improved fitness in Hodgkin lymphoma survivors. 70 In a 12-month home-based aerobic and resistance training RCT, Moyer-Mileur et al 44 found a significant increase in self-reported physical activity and fitness, but no increase in objectively measured physical activity (pedometer-measured steps). A small intervention study that included supervised and home-based exercise increased physical activity.…”
Section: Adultsmentioning
confidence: 99%
“…Twelve studies, [42][43][44][45][46][47][48][68][69][70][71][72] including two RCT 42,44 and seven high-quality studies [42][43][44][45][46]69,71 evaluated the effects of physical activity interventions on outcomes in children with pediatric cancer who did not undergo HSCT. One study of high quality 68 evaluated the effects of a single (30 min) exercise bout.…”
Section: Adultsmentioning
confidence: 99%
“…Despite improving fitness, interventions have not improved body composition. 42,70,72 As noted above, significant interest in the effects of exercise on blood markers exists for these patients. Marchese et al 69 reported no change in hemoglobin in ALL survivors (4-15 years) participating in aerobic and resistance training.…”
Section: Adultsmentioning
confidence: 99%
“…However, a 20-week aerobic intervention of thrice weekly activity for 30-40 min after treatment reduced fatigue in Hodgkin lymphoma survivors. 70 Finally, Shore and Shepard 48 reported that a 12-week aerobic intervention of 30 min of Outcomes examined in at least two studies.…”
Observational research has shown that the physical activity levels of survivors of hematological cancer are low, with deleterious health consequences. This review summarizes the research on exercise interventions in adult and pediatric hematological cancer survivors. We searched MEDLINE, SPORTDiscus, CINAHL, Embase, Cochrane and PEDro through September 2009 for exercise intervention studies in children and adults with any type of hematological cancer. In the 24 adult intervention studies reviewed, we found strong evidence (that is, X3 high-quality studies and X75% reporting a significant benefit) for a benefit on body composition. Weak, but promising, evidence (X3 high-quality studies, but o75% reporting a significant benefit) was found for cardiorespiratory fitness, fatigue, muscle strength, physical functioning and quality of life. In pediatric interventions (13 studies), we found strong evidence for a benefit on muscle strength and cardiorespiratory fitness, particularly, if training was conducted in the hospital setting. Evidence is weak for ankle dorsiflexion, physical functioning and body composition. No exerciserelated risks were identified in adults or children studies. Though more randomized controlled trials are needed, a growing body of literature supports the notion that regular physical activity is safe and has potential benefits for both adult and pediatric hematological cancer survivors.
“…18 These recruiting challenges may also result in reduced generalizability of the study sample. Oldervall et al 70 found that consenters had higher education, a concern as those of lower socioeconomic status tend to do worse on most health indicators. As noted above, several studies only analyzed those who remained in the study at follow-up or who adhered to the intervention.…”
Section: Discussionmentioning
confidence: 99%
“…A 20-week aerobic intervention of thrice weekly activity for 30-40 min after treatment improved fitness in Hodgkin lymphoma survivors. 70 In a 12-month home-based aerobic and resistance training RCT, Moyer-Mileur et al 44 found a significant increase in self-reported physical activity and fitness, but no increase in objectively measured physical activity (pedometer-measured steps). A small intervention study that included supervised and home-based exercise increased physical activity.…”
Section: Adultsmentioning
confidence: 99%
“…Twelve studies, [42][43][44][45][46][47][48][68][69][70][71][72] including two RCT 42,44 and seven high-quality studies [42][43][44][45][46]69,71 evaluated the effects of physical activity interventions on outcomes in children with pediatric cancer who did not undergo HSCT. One study of high quality 68 evaluated the effects of a single (30 min) exercise bout.…”
Section: Adultsmentioning
confidence: 99%
“…Despite improving fitness, interventions have not improved body composition. 42,70,72 As noted above, significant interest in the effects of exercise on blood markers exists for these patients. Marchese et al 69 reported no change in hemoglobin in ALL survivors (4-15 years) participating in aerobic and resistance training.…”
Section: Adultsmentioning
confidence: 99%
“…However, a 20-week aerobic intervention of thrice weekly activity for 30-40 min after treatment reduced fatigue in Hodgkin lymphoma survivors. 70 Finally, Shore and Shepard 48 reported that a 12-week aerobic intervention of 30 min of Outcomes examined in at least two studies.…”
Observational research has shown that the physical activity levels of survivors of hematological cancer are low, with deleterious health consequences. This review summarizes the research on exercise interventions in adult and pediatric hematological cancer survivors. We searched MEDLINE, SPORTDiscus, CINAHL, Embase, Cochrane and PEDro through September 2009 for exercise intervention studies in children and adults with any type of hematological cancer. In the 24 adult intervention studies reviewed, we found strong evidence (that is, X3 high-quality studies and X75% reporting a significant benefit) for a benefit on body composition. Weak, but promising, evidence (X3 high-quality studies, but o75% reporting a significant benefit) was found for cardiorespiratory fitness, fatigue, muscle strength, physical functioning and quality of life. In pediatric interventions (13 studies), we found strong evidence for a benefit on muscle strength and cardiorespiratory fitness, particularly, if training was conducted in the hospital setting. Evidence is weak for ankle dorsiflexion, physical functioning and body composition. No exerciserelated risks were identified in adults or children studies. Though more randomized controlled trials are needed, a growing body of literature supports the notion that regular physical activity is safe and has potential benefits for both adult and pediatric hematological cancer survivors.
Background Cancer-related fatigue is recognised as an important symptom associated with cancer and its treatment. A number of studies have investigated the effects of physical activity in reducing cancer-related fatigue. This is an updated version of the original Cochrane review published in The Cochrane Library (2008, Issue 1). The original review identified some benefits of physical activity on fatigue in cancer both during and after adjuvant treatment. We identified a number of limitations in the evidence, providing clear justification for an updated review. Objectives To evaluate the effect of exercise on cancer-related fatigue both during and after cancer treatment.
Background Cancer-related fatigue is recognised as an important symptom associated with cancer and its treatment. A number of studies have investigated the effects of physical activity in reducing cancer-related fatigue. This is an updated version of the original Cochrane review published in The Cochrane Library (2008, Issue 1). The original review identified some benefits of physical activity on fatigue in cancer both during and after adjuvant treatment. We identified a number of limitations in the evidence, providing clear justification for an updated review. Objectives To evaluate the effect of exercise on cancer-related fatigue both during and after cancer treatment.
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