“…They are also effective and have been associated with a clinically significant effect on nasal congestion for nonallergic rhinitis 336-338 but Antihistamine, oral with decongestant, oral (SS 63) More effective relief of nasal congestion than antihistamines alone Antihistamine, oral with LTRA, oral (SS 85) May be more effective than monotherapy with antihistamine or LTRA Less effective than INS An alternative treatment for patients unresponsive to or not compliant with INS Antihistamine, oral with intranasal antihistamine (SS [65][66][67][68][69] Combination may be considered, although controlled studies of additive benefit lacking Antihistamine, oral with intranasal corticosteroids (SS [74][75][76][77] Combination may be considered, although supporting studies limited and many studies unsupportive of additive benefit of adding an antihistamine to an intranasal steroid Intranasal anticholinergic with intranasal corticosteroid (SS 84) Concomitant use of ipratropium bromide nasal spray and an intranasal corticosteroid is more effective for rhinorrhea than administration of either drug alone Intranasal antihistamine with intranasal corticosteroid (SS 65-69) Combination may be considered based on limited data Inadequate data about optimal interval between administration of the 2 sprays For mixed rhinitis, there may be significant added benefit to the combination of an intranasal antihistamine with an intranasal corticosteroid LTRA, oral with intranasal corticosteroid (SS 85) Subjective additive relief in limited studies, data inadequate are generally less effective than intranasal corticosteroid for treatment of allergic rhinitis. 46 Combination therapy with intranasal corticosteroids may provide added benefit.…”