Exercise in the Management of Obesity

Moinuddin, Irfan; Collins, Eileen G.; Kramer, Holly

doi:10.4172/2165-7904.1000117

Cited by 7 publications

(15 citation statements)

References 85 publications

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“…Previous studies have shown the potential benefits of exercise for obesity treatment due to its effects on energy expenditure, modulation of body composition, and enhancement of physical performance [23][24][25]. Additionally, previous studies have shown the potential relationship between higher physical activity levels and longer TL in leukocytes [25][26][27] and skeletal muscle cells [28,29].…”

Section: Discussionmentioning

confidence: 99%

The effects of short-term combined exercise training on telomere length in obese women: a prospective, interventional study

et al. 2020

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Background Telomere length is inversely associated with the senescence and aging process. Parallelly, obesity can promote telomere shortening. Evidence suggests that physical activity may promote telomere elongation. Objective This study’s objective is to evaluate the effects of combined exercise training on telomere length in obese women. Design and Methods Twenty pre-menopausal women (BMI 30–40 kg/m2, 20–40 years) submitted to combined training (strength and aerobic exercises), but only 13 finished the protocol. Each exercise session lasted 55 min/day, three times a week, throughout 8 weeks. Anthropometric data, body composition, physical performance (Vo2max), and 8-h fasting blood samples were taken before and after 8 weeks of training. Leukocyte DNA was extracted for telomere length by RT-qPCR reaction, using the 2−ΔΔCt methodology. Results After the training intervention, significant differences (p < 0.05) were observed in telomere length (respectively before and after, 1.03 ± 0.04 to 1.07 ± 0.04 T/S ratio), fat-free mass (46 ± 7 to 48 ± 5 kg), Vo2max (35 ± 3 to 38 ± 3 ml/kg/min), and waist circumference (96 ± 8 to 90 ± 6 cm). In addition, an inverse correlation between waist circumference and telomere length was found, before (r = − 0.536, p = 0.017) and after (r = − 0.655, p = 0.015) exercise training. Conclusion Combined exercise promoted leukocyte telomere elongation in obese women. Besides, the data suggested that greater waist circumference may predict shorter telomere length. Clinical Trial Registration ClinicalTrails.gov, NCT03119350. Retrospectively registered on 18 April 2017

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Section: Discussionmentioning

confidence: 99%

The effects of short-term combined exercise training on telomere length in obese women: a prospective, interventional study

et al. 2020

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“…Some clinical guidelines include an even greater increase in physical activity (300 min/week of moderate-intensity exercise or 150 min/week of vigorous exercise) to achieve more extensive health benefi ts. Respiratory impairments related to simple obesity have been well described and include reduced lung volumes, decreased chest wall compliance, increased respiratory resistance, and increased work of breathing [4].…”

Section: Introductionmentioning

confidence: 99%

The impact of obesity on walking and physical performance

Youssef

2014

Egypt J Intern Med

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Twenty obese participants were included in this study. Their ages ranged from 25 to 43 years. All participants were evaluated before the fi rst session of physical therapy program and at the end of the program after 2 months of exercise and a low-caloric diet of 25 kcal/kg actual weight/day through physical evaluation, which included anthropometric measurements, BMI, inspiratory capacity, and a physical performance test, which includes four tests (15-m rapid walking test, a timed up-and-go test, and stair climbing and stair descending tests). ResultsAnalysis of data revealed signifi cant improvement in the parameters assessed as follows: weight decreased from 81.3 ± 8.5 to 68.00 ± 4.50 kg (P ≤ 0.001); BMI decreased from 29.8 ± 2.0 to 24.1 ± 2.0 kg/m 2 (P ≤ 0.001); waist circumference decreased from 120.3 ± 14.4 to 112.3 ± 9.6 cm (P = 0.053); hip circumference decreased from 121.3 ± 6.1 to 112.6 ± 11.4 cm (P = 0.009); inspiratory capacity increased from 14.4 ± 2.7 to 21.0 ± 2.3 s (P ≤ 0.001); time of 15 m walk decreased from 21.2 ± 1.7 to 15.5 ± 2.1 s; timed up-and-go test decreased from 24.1 ± 2.8 to 15.3 ± 2.3 s; stair climbing time decreased from 45.3 ± 6.5 to 34.2 ± 2.6 s; stair descending time decreased from 36.2 ± 2.3 to 27.2 ± 2.1 s. Hence, the total physical performance increased from 31.9 ± 10.3 to 23.0 ± 8.5 s (P ≤ 0.001) and consequently improved the quality of life. ConclusionLifestyle modifi cation in the form of a low-caloric diet accompanied by exercise has a positive effect on physical performance and consequently on the quality of life.

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“…Specifically, exercise accelerates the breakdown of glycogen in the muscles and liver; this promotes the breakdown of fat in adipose tissue and muscle; and facilitates the oxidation of fatty acids in muscles (Poirier and Després, 2001). All these effects are mediated through hormone stimulation, secretion and substrate concentration, leading to enzyme activation, which is a key step in the catalytic energy catabolism pathway (Moinuddin et al, 2012). Typically, according to a previous study demonstrating that exercising about 60 min at moderate training more than 4 days a week, individuals will lose 0.5 lb per week (Poirier and Després, 2001).…”

Section: Exercise Benefits For Health and Covid-19mentioning

confidence: 99%

A Preventive Role of Exercise Across the Coronavirus 2 (SARS-CoV-2) Pandemic

et al. 2020

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The coronavirus 2019 (COVID-19) pandemic has posed a significant threat to human health around the world. A severe risk of infection has been observed in elderly populations. In addition, individuals with obesity and obesity-related comorbidities have also been identified to be at a higher risk of infection for COVID-19. We have attempted here to provide evidence in support of exercise management as a prevention strategy for improving health and minimizing the effects of COVID-19. Therefore, exercise duration, frequency, and intensity benefits are summarized in an attempt to provide guidelines for the general population. In terms of exercise effects, there are multiple benefits of exercise related to human health. These include, decreases in adipose tissue, improvements in cardio-respiratory fitness, enhanced metabolic homeostasis, and suppress inflammation active. With respect to the amount of exercise performed individuals should exercise at a moderate intensity for at least 150 min/wk as an initial target. Increases in intensity and duration of exercise training are necessary for significant fitness benefits, weight loss, and prevention of weight regain. In relation to walking, 10,000 steps/day at a rate of 64-170 steps/minute for at least 10 min duration is reasonable for healthy adults. For exercise intensity, a combination of resistance training (RT), aerobic training (AT) as well as high-intensity interval training (HIIT) incorporated with moderate-intensity continuous training (MICT) can be recognized as an optimal exercise mode for health benefits. Aerobic training and MICT should be viewed as a basis for exercise in combination with appropriate volumes and types of RT and HIIT. Activities should be performed according to professional guidelines and advice. If implemented, these measures may reduce infection rates, underlying pathologies, and assist in decreasing mortality associated with COVID-19 pandemic.

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Exercise in the Management of Obesity

Cited by 7 publications

References 85 publications

The effects of short-term combined exercise training on telomere length in obese women: a prospective, interventional study

The effects of short-term combined exercise training on telomere length in obese women: a prospective, interventional study

The impact of obesity on walking and physical performance

A Preventive Role of Exercise Across the Coronavirus 2 (SARS-CoV-2) Pandemic

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