Exercise and Inflammatory Bowel Disease

Narula, Neeraj; Fedorak, Richard N.

doi:10.1155/2008/785953

Cited by 73 publications

(59 citation statements)

References 60 publications

(55 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…There is no evidence of negative side effects of moderate PA in stable IBD patients [22,34,35]. Furthermore, data suggest that especially extra-intestinal aspects of IBD (e.g.…”

Section: Discussionmentioning

confidence: 99%

The Impact of a Ten-Week Physical Exercise Program on Health-Related Quality of Life in Patients with Inflammatory Bowel Disease: A Prospective Randomized Controlled Trial

Klare¹,

Nigg²,

Nold³

et al. 2015

Digestion

158

130

View full text Add to dashboard Cite

Background: Improving health-related quality of life is a primary target of therapy for patients with inflammatory bowel disease. Physical activity has been demonstrated to improve health-related quality of life in several patient populations with chronic disease. There are very few studies investigating the effects of physical activity on health-related quality of life in inflammatory bowel disease. The primary purpose of this study is to investigate the effects of 10 weeks of moderate physical activity on health-related quality of life in patients with inflammatory bowel disease. Methods: Thirty patients with mild to moderate IBD (Crohn‘s Disease Activity Index (CDAI) <220 or Rachmilewitz Index (RI) <11) were randomized 1:1 to either supervised moderate-intensity running thrice a week for 10 weeks or a control group who were not prescribed any exercise. Health-related quality of life, symptoms, and inflammation were assessed at baseline and after 10 weeks. Results: Participants were 41 ± 14 years (73% female), had a body mass index of 22.8 ± 4.1 kg/m², and an average CDAI or RI of 66.8 ± 42.4 and 3.6 ± 3.1. No adverse events occurred during the 10-week training period. Health-related quality of life, reported as IBDQ total score, improved 19% in the intervention group and 8% in the control group. Scores for the IBDQ social sub-scale were significantly improved in the intervention group compared with controls (ΔIBDQ_social = 6.27 ± 5.46 vs. 1.87 ± 4.76, p = 0.023). Conclusion: Patients suffering from moderately active IBD are capable of performing symptom-free regular endurance exercise. Our data support the assumption that PA is feasible in IBD patients. PA may furthermore improve quality of life through improvements in social well-being, and may, therefore, be a useful adjunct to IBD therapy.

show abstract

“…There is no evidence of negative side effects of moderate PA in stable IBD patients [22,34,35]. Furthermore, data suggest that especially extra-intestinal aspects of IBD (e.g.…”

Section: Discussionmentioning

confidence: 99%

The Impact of a Ten-Week Physical Exercise Program on Health-Related Quality of Life in Patients with Inflammatory Bowel Disease: A Prospective Randomized Controlled Trial

Klare¹,

Nigg²,

Nold³

et al. 2015

Digestion

158

130

View full text Add to dashboard Cite

show abstract

“…41 Patients who have had surgical resection may have diminished exercise capacity commensurate with the amount of intestine resected. 42, 43 These factors might prevent patients with IBD from reaping the known benefits of exercise. Exercise may improve skeletal health and has been shown to improve bone mineral density in patients with IBD.…”

Section: Discussionmentioning

confidence: 99%

Exercise Decreases Risk of Future Active Disease in Patients with Inflammatory Bowel Disease in Remission

Jones

Kappelman

Martin

et al. 2015

Inflammatory Bowel Diseases

View full text Add to dashboard Cite

Background Although exercise impacts quality of life in patients with inflammatory bowel disease (IBD), little is known about its role in disease activity. Among IBD patients in remission, we aimed to evaluate the association between exercise and subsequent active disease. Methods We performed a prospective study using the Crohn's and Colitis Foundation of America (CCFA) Partners Internet-based cohort of individuals with self-reported IBD. We identified participants in remission, defined as short Crohn's disease activity index (sCDAI) <150 or simple clinical colitis activity index (SCCAI) ≤2. The primary exposure was exercise status, measured using the validated Godin leisure time activity index. The primary study outcome, assessed after six months, was active disease defined using the above disease activity index thresholds. We used bivariate and multivariate analyses to describe the independent association between exercise and risk of active disease. Results We identified 1308 patients with Crohn's Disease (CD) and 549 with ulcerative or indeterminate colitis (UC/IC) in remission, of whom 227(17.4%) with CD and 135 (24.6%) with UC/IC developed active disease after 6 months. Higher exercise level was associated with decreased risk of active disease for CD (adjusted RR 0.72, 95% CI 0.55-0.94) and UC/IC (adjusted RR 0.78, 95% CI 0.54-1.13). Conclusions In patients with CD in remission, those with higher exercise levels were significantly less likely to develop active disease at six months. In patients with UC/IC in remission, patients with higher exercise levels were less likely to develop active disease at six months, however this was not statistically significant.

show abstract

“…84 It is noted that care must be taken in determining the intensity of exercise that is most helpful. In 1 study, 32 adults with either mild or inactive IBD were randomized to low-intensity exercise (walking) or no exercise and followed over 3 months.…”

Section: Exercise and Sleepmentioning

confidence: 99%

Strategies to improve quality of life in adolescents with inflammatory bowel disease

Karwowski

Keljo

Szigethy

2009

Inflammatory Bowel Diseases

View full text Add to dashboard Cite

Inflammatory bowel disease (IBD), which encompasses Crohn's disease (CD) and ulcerative colitis (UC), are chronic and debilitating conditions with unpredictable courses and complicated treatment. Pediatric IBD carries implications that extend beyond the health of the gastrointestinal tract. When these lifelong illnesses are diagnosed during adolescence, a critical developmental period, the transition to adulthood can be even more turbulent. Like other chronic diseases of childhood, patients with IBD are at risk for depression, anxiety, social isolation, and altered self-image, which can all negatively affect health-related quality of life (HRQOL). The review will draw from pertinent adult and pediatric literature about HRQOL over the past 10 years using a PubMed literature search to summarize instruments with which HRQOL is measured, and address factors that affect HRQOL in adolescents and young adults with IBD. Psychosocial interventions that have been utilized to improve quality of life in this population will also be covered. Identifying patients with impaired quality of life is of paramount importance, as is implementing strategies that may improve HRQOL, so that they may have an easier transition to adulthood while living with IBD.

show abstract

Exercise and Inflammatory Bowel Disease

Cited by 73 publications

References 60 publications

The Impact of a Ten-Week Physical Exercise Program on Health-Related Quality of Life in Patients with Inflammatory Bowel Disease: A Prospective Randomized Controlled Trial

The Impact of a Ten-Week Physical Exercise Program on Health-Related Quality of Life in Patients with Inflammatory Bowel Disease: A Prospective Randomized Controlled Trial

Exercise Decreases Risk of Future Active Disease in Patients with Inflammatory Bowel Disease in Remission

Strategies to improve quality of life in adolescents with inflammatory bowel disease

Contact Info

Product

Resources

About