Exclusive nodal recurrence after treatment of degenerated parietal endometriosis

Bourdel, Nicolas; Durand, Maud; Gimbergues, Pierre; Dauplat, J.; Canis, Michel

doi:10.1016/j.fertnstert.2009.11.004

Cited by 16 publications

(14 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Twenty‐seven cases of malignancy arising in a focus of scar endometriosis (mostly in abdominal wall), including the present case, have been reported in the literature between January 1966 and November 2011 and are summarized in Table . Of these 28 total cases, 18 showed clear cell carcinoma, 4 showed endometrioid carcinoma, 2 had papillary serous carcinoma, 1 reported carcinosarcoma and 1 reported adenocarcinoma.…”

Section: Discussionmentioning

confidence: 92%

Clear cell adenocarcinoma arising from endometriosis in abdominal wall cesarean section scar: a case report and review of the literature

et al. 2012

View full text Add to dashboard Cite

Malignancy arising in association with endometriosis is a rare but well-documented phenomenon that was first described in the literature as early as 1925. Cutaneous endometriosis with subsequent malignant transformation is even more uncommon, and high clinical suspicion is required for diagnosis. The clinical differential diagnosis of these lesions includes a wide variety of entities, ranging from benign cysts to malignancies such as melanoma. We report a case of clear cell adenocarcinoma arising from endometriosis in a cesarean section scar in a 47-year-old woman, and we complete a review of the literature regarding this unusual entity.

show abstract

Section: Discussionmentioning

confidence: 92%

Clear cell adenocarcinoma arising from endometriosis in abdominal wall cesarean section scar: a case report and review of the literature

et al. 2012

View full text Add to dashboard Cite

show abstract

“…However, it has to be considered that four patients had referred cyclic pain in the CS scar during menses, or the cyclic increase/decrease of the mass volume, which could be highly suggestive of the presence of endometriosis implants [14, 17, 19, 23]. Moreover, previous history of the excision of benign endometriosis foci at the CS scar was reported in five cases [9, 11, 13, 15, 16]. Therefore, the absence of pathologically assessed endometriosis foci could be interpreted as either a sampling problem or a consequence of the complete replacement of normal tissue due to massive neoplastic proliferation.…”

Section: Discussionmentioning

confidence: 99%

“…It has to be acknowledged that of 9 cases undergoing lymphadenectomy or sampling, 8 showed diffuse metastatic involvement of inguinal, and/or pelvic, and/or aortic lymph nodes ([11, 14, 15, 19, 22, 23] current case).…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Endometriosis-associated clear cell carcinoma arising in caesarean section scar: a case report and review of the literature

et al. 2016

View full text Add to dashboard Cite

BackgroundMalignant transformation has been reported in approximately 1% of the endometriosis cases; herein, we report a case of clear cell endometrial carcinoma arising from endometriosis foci located within a caesarean section scar.Case presentationIn November 2014, a Caucasian, 44-year-old woman was transferred to our institution because of severe respiratory failure due to massive lung embolism and rapid enlargement of a subcutaneous suprapubic mass. Abdomino-pelvic magnetic resonance showed a 10.5 × 5.0 × 5.0 cm subcutaneous solid mass involving the rectus abdominis muscle. Pelvic organs appeared normal, while right external iliac lymph nodes appeared enlarged (maximum diameter = 16 mm). A whole-body positron emission tomography/computed tomography scan showed irregular uptake of the radiotracer in the 22 cm mass of the abdominal wall, and in enlarged external iliac and inguinal lymph nodes. In December 2014, the patient underwent exploratory laparoscopy showing normal adnexae and pelvic organs; peritoneal as well as cervical, endometrial and vesical biopsies were negative. The patient was administered neo-adjuvant chemotherapy with carboplatin and paclitaxel, weekly, without benefit and then underwent wide resection of the abdominal mass, partial removal of rectus abdominis muscle and fascia, radical hysterectomy, bilateral salpingo-oophorectomy, and inguinal and pelvic lymphadenectomy. The muscular gap was repaired employing a gore-tex mesh while the external covering was made by a pedicled perforator fasciocutaneous anterolateral thigh flap. Final diagnosis was clear cell endometrial adenocarcinoma arising from endometriosis foci within the caesarean section scar. Pelvic and inguinal lymph nodes were metastatic. Tumor cells were positive for CK7 EMA, CKAE1/AE3, CD15, CA-125, while immunoreaction for Calretinin, WT1, estrogen, and progesterone receptors, cytokeratin 20, CD10, alpha fetoprotein, CDX2, TTF1, and thyroglobulin were all negative. Liver relapse occurred after 2 months; despite 3 cycles of pegylated liposomal doxorubicin (20 mg/m2, biweekly administration), the death of the patient disease occurred 1 month later.ConclusionsAttention should be focused on careful evaluation of patient history in terms of pelvic surgery, and symptoms suggestive of endometriosis such as repeated occurrence of endometriosis nodules at CS scar, or cyclic pain, or volume changes of the nodules.

show abstract

“…One reason for this difference may be the fact that abdominal wall cancer seems to be more locally advanced at the time of diagnosis. In addition, 3 patients showed lymph node invasion and died within 30 months after surgery, 23,24,31 suggesting that lymph node invasion is a negative prognostic factor for patient survival.…”

Section: Discussionmentioning

confidence: 99%

Endometriosis-Associated Abdominal Wall Cancer: A Poor Prognosis?

Taburiaux

Pluchino

Petignat

et al. 2015

Int J Gynecol Cancer

View full text Add to dashboard Cite

show abstract

Exclusive nodal recurrence after treatment of degenerated parietal endometriosis

Cited by 16 publications

References 24 publications

Clear cell adenocarcinoma arising from endometriosis in abdominal wall cesarean section scar: a case report and review of the literature

Clear cell adenocarcinoma arising from endometriosis in abdominal wall cesarean section scar: a case report and review of the literature

Endometriosis-associated clear cell carcinoma arising in caesarean section scar: a case report and review of the literature

Endometriosis-Associated Abdominal Wall Cancer: A Poor Prognosis?

Contact Info

Product

Resources

About