Excitatory amino acid transporters in the zebrafish

Gesemann, Matthias; Maurer, Colette M.

doi:10.1016/j.brainresbull.2010.04.018

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Section Ii: Effects Of CD and Hg On Fish1

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Cited by 9 publications

(2 citation statements)

References 22 publications

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“…The zebrafish genome harbors two eaat2 genes that originated from a whole-genome duplication event ∼350 million years ago (Gesemann et al, 2010b). For EAAT2, we found an unusual case of both spatial and functional subfunctionalization (division of the ancestral gene function among the two paralogs, as reviewed by Glasauer and Neuhauss [2014]).…”

Section: Introductionmentioning

confidence: 99%

Shaping of Signal Transmission at the Photoreceptor Synapse by EAAT2 Glutamate Transporters

Niklaus

Cadetti

Berg

et al. 2017

eNeuro

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Section: Introductionmentioning

confidence: 99%

Shaping of Signal Transmission at the Photoreceptor Synapse by EAAT2 Glutamate Transporters

Niklaus

Cadetti

Berg

et al. 2017

eNeuro

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“…The genome of zebrafish was fully sequenced and expressed more than 70% of homology with the human genome [140] . Also, amino acid sequences of functionally relevant proteins are highly conserved in Zebrafish [141] , [142] . It was demonstrated that zebrafish possessed orthologues for 86% of human drug targets [143] which is why the fish is now being well used to discover novel pathways and toxicity mechanisms to investigate human diseases [144] .…”

Section: Section Ii: Effects Of CD and Hg On Fishmentioning

confidence: 99%