Abstract:We read with great interest the review entitled Best Practice in Intravascular Lithotripsy by Honton and Monsegui published recently in Interventional Cardiology. 1 We fully agree with the authors on the benefits of intravascular lithotripsy (IVL), a technology that has changed the treatment of calcified lesions because of its safety and efficacy, as well as having potential advantages over other plaque modification techniques. Its main limitation is the crossing profile when treating a very tight and sever… Show more
“…[ 24 ] The authors agree with Vera-Vera et al, who had some specific suggestions to the proposed algorithm, namely the use of ELCA in moderate/severe calcified lesions. [ 25 ] The authors believe that in the specific subset of patients presenting with severe stent under-expansion, after failure of NC ballooning and rotablation, it would be reasonable to use ELCA subsequently followed by the use of super high-pressure balloon. As described above OPN NC balloon behaves as a regular NC balloon under 30 atm.…”
Section: Plaque and Calcification Modifying Techniques And Toolsmentioning
confidence: 99%
“…These algorithm options are proposed for highly calcified, resistant lesions, but can be partially applied in stent under-expansion treatment. [ 24 , 25 ] Once the vessel preparation is complete, the lesion can be treated according to guidelines as it was in the present case. [ 26 , 27 ]…”
Section: Plaque and Calcification Modifying Techniques And Toolsmentioning
Patients with calcified, fibrotic native coronary vessels with prior suboptimal stenting outcomes are at major risk of stent thrombosis and could face serious consequences if untreated. In cases of multiple layers of under-expanded stents, the risk is multiplied. If conventional balloon post-dilatation is unsuccessful after stent implantation without proper lesion preparation, few interventional options remain. The authors report on a patient with prior numerous right coronary unsuccessful coronary interventions resulting in partially crushed multiple layers of stent material with critical lumen narrowing caused by stent under-expansion. Balloon angioplasty and stent rotational atherectomy (ROTA) had been attempted to overcome stent under-expansion but were unsuccessful. The authors investigated a new combination therapy of laser atherectomy (ELCA) and super high-pressure balloon (OPN non-compliant balloon) to treat single or multiple layers of stent with severe under-expansion due to fibrotic, calcified tissue surrounding the under-expanded stent structure.
“…[ 24 ] The authors agree with Vera-Vera et al, who had some specific suggestions to the proposed algorithm, namely the use of ELCA in moderate/severe calcified lesions. [ 25 ] The authors believe that in the specific subset of patients presenting with severe stent under-expansion, after failure of NC ballooning and rotablation, it would be reasonable to use ELCA subsequently followed by the use of super high-pressure balloon. As described above OPN NC balloon behaves as a regular NC balloon under 30 atm.…”
Section: Plaque and Calcification Modifying Techniques And Toolsmentioning
confidence: 99%
“…These algorithm options are proposed for highly calcified, resistant lesions, but can be partially applied in stent under-expansion treatment. [ 24 , 25 ] Once the vessel preparation is complete, the lesion can be treated according to guidelines as it was in the present case. [ 26 , 27 ]…”
Section: Plaque and Calcification Modifying Techniques And Toolsmentioning
Patients with calcified, fibrotic native coronary vessels with prior suboptimal stenting outcomes are at major risk of stent thrombosis and could face serious consequences if untreated. In cases of multiple layers of under-expanded stents, the risk is multiplied. If conventional balloon post-dilatation is unsuccessful after stent implantation without proper lesion preparation, few interventional options remain. The authors report on a patient with prior numerous right coronary unsuccessful coronary interventions resulting in partially crushed multiple layers of stent material with critical lumen narrowing caused by stent under-expansion. Balloon angioplasty and stent rotational atherectomy (ROTA) had been attempted to overcome stent under-expansion but were unsuccessful. The authors investigated a new combination therapy of laser atherectomy (ELCA) and super high-pressure balloon (OPN non-compliant balloon) to treat single or multiple layers of stent with severe under-expansion due to fibrotic, calcified tissue surrounding the under-expanded stent structure.
“…Excimer laser coronary atherectomy (ELCA) is an established adjunctive technique to facilitate acute success in percutaneous coronary intervention (PCI). [1][2][3][4][5][6] The main indications for the use of ELCA during PCI are targeted at lesion preparation. These include management of uncrossable stenoses and undilatable lesions, debulking in stent restenosis (ISR) and optimizing under-expanded stents and finally ablation of thrombus.…”
Section: Introductionmentioning
confidence: 99%
“…These include management of uncrossable stenoses and undilatable lesions, debulking in stent restenosis (ISR) and optimizing under-expanded stents and finally ablation of thrombus. [1][2][3][4][6][7][8] Through the development of ELCA technology and improvements in operator technique this tool has established a role in many complex PCI algorithms. 1,3,5 Despite the relatively simple learning curve for an atherectomy device, ELCA use has mainly been limited to a few selected high-volume PCI centers largely due to fiscal considerations.…”
Section: Introductionmentioning
confidence: 99%
“…Excimer laser coronary atherectomy (ELCA) is an established adjunctive technique to facilitate acute success in percutaneous coronary intervention (PCI) 1–6 . The main indications for the use of ELCA during PCI are targeted at lesion preparation.…”
BackgroundExcimer laser atherectomy (ELCA) is an established adjunctive technique to facilitate acute success in percutaneous coronary intervention (PCI). Despite this there are a lack of contemporary outcome data, particulary longer‐term, forpatients treated with ELCA PCI.AimsTo evaluate the contemporary use ofELCA in PCI, the frequency of periprocedural complications and the longer‐term outcomes associated with ELCA PCI.MethodsThis was a retrospective study that included all patients undergoing PCI (with or without ELCA) between April 2005 and May 2021. Relevant features from all cases were downloaded from the patient record and matched to hospital data on mortality on November 22, 2022. Kaplan Meier curves were used to compare mortality between the ELCA PCI and non‐ELCA PCI cohorts with a landmark at 1 year. Multivariable Cox regression was performed to assess whether ELCA PCI was independently associated with long‐term mortality.ResultThere were 21,256 patients in this analysis, of which 448 (2.1%) were treated with ELCA PCI. ELCA PCI was associated with a higher frequency of any periprocedural complication. Median follow‐up was 2812 days (IQR, 1577–4245 days) with higher mortality in ELCA PCI (38.2% vs. 29.0%, p < 0.001). However, on multivariable analysis, ELCA PCI was not independently associated with long‐term mortality. The TVR frequency in ELCA PCI was 16.7% but TVR was significantly higher for cases of in‐stent restenosis (ISR) (29.5%).ConclusionDespite ELCA PCI being used in higher risk populations with complex coronary artery disease there was no long‐term increased mortality associated with the use of this device. ELCA PCI for ISR is highly effective and safe although TVR in this cohort remains high in long‐term follow‐up.
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