Excess of body weight is associated with accelerated T-cell senescence in hospitalized COVID-19 patients
Mailton Prestes Madruga,
Lucas Kich Grun,
Letícya Simone Melo Dos Santos
et al.
Abstract:Background
Several risk factors have been involved in the poor clinical progression of coronavirus disease-19 (COVID-19), including ageing, and obesity. SARS-CoV-2 may compromise lung function through cell damage and paracrine inflammation; and obesity has been associated with premature immunosenescence, microbial translocation, and dysfunctional innate immune responses leading to poor immune response against a range of viruses and bacterial infections. Here, we have comprehensively characteriz… Show more
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