2022
DOI: 10.2105/ajph.2022.307096
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Excess Mortality From Non–COVID-19 Causes During the COVID-19 Pandemic in Philadelphia, Pennsylvania, 2020–2021

Abstract: Objectives. To estimate excess mortality from non–COVID-19 causes during the COVID-19 pandemic in Philadelphia, Pennsylvania, and understand disparities by race/ethnicity, age, and sex. Methods. We used Poisson regression models of weekly deaths using data from Pennsylvania’s vital registration system (2018–2021). Results. There was significant excess mortality as a result of heart disease, homicide, diabetes, drug overdoses, traffic crashes, and falls in 2020–2021; the burden of this excess non–COVID-19 mor… Show more

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Cited by 8 publications
(5 citation statements)
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“…In the analysis of age-and gender-adjusted mortality rate ratios based on causes of death, several signi cant differences between reference period were identi ed. Consistent with the ndings of several other studies, this study revealed that mortality from circulatory system diseases was higher during the pandemic period (16)(17)(18)(19)31). In 2021, mortality from cardiovascular diseases was 1.06 times higher (95% CI 1.03-1.09) than in 2018-2019.…”
Section: Discussionsupporting
confidence: 90%
See 1 more Smart Citation
“…In the analysis of age-and gender-adjusted mortality rate ratios based on causes of death, several signi cant differences between reference period were identi ed. Consistent with the ndings of several other studies, this study revealed that mortality from circulatory system diseases was higher during the pandemic period (16)(17)(18)(19)31). In 2021, mortality from cardiovascular diseases was 1.06 times higher (95% CI 1.03-1.09) than in 2018-2019.…”
Section: Discussionsupporting
confidence: 90%
“…In some countries delayed access to medical care has led to increased mortality in various diseases (17,18). Several studies have identi ed an increase in mortality from cardiovascular diseases during the Covid-19 pandemic (17)(18)(19). Therefore it could be suspected that the distribution of causes of death during the pandemic period has changed for reasons other than just the addition of Covid-19-related deaths.…”
mentioning
confidence: 99%
“…The decline mainly concerned deaths from diseases of the respiratory system, diseases of the nervous system and sense organs, and tumors [30,31]. In contrast, studies in the United States observed a rise in non-COVID-19 mortality in the general population during the pandemic, in particular for circulatory diseases, diabetes, external causes and drug-or alcohol-induced causes [32][33][34][35].…”
Section: Discussionmentioning
confidence: 99%
“…These concerning results were further elucidated by Aarstad and Kvitastein, who found that among 31 countries in Europe, a higher population COVID-19 vaccine uptake in 2021 was positively correlated with increased all-cause mortality in the first nine months of 2022 after controlling for alternative explanations 71 . Furthermore, excess mortality from non-COVID-19 causes has been detected in many countries since the mass vaccination programs began 72,73,74,75,76,77 , suggesting a common deleterious exposure among populations. Pantazatos estimated that VAERS deaths are underreported by a factor of 20 69 .…”
Section: Discussionmentioning
confidence: 99%