Excess mortality among people with podoconiosis: secondary analysis of two Ethiopian cohorts

Masraf, Hannah; Azemeraw, Temesgen; Molla, Meseret Derbew; Jones, Christopher I.; Bremner, Stephen; Ngari, Moses; Berkley, James A.; Kivaya, Esther; Fegan, Greg; Tamiru, Abreham; Kelemework, Abebe; Lang, Trudie; Newport, Melanie; Davey, Gail

doi:10.1093/trstmh/traa150

Cited by 6 publications

(5 citation statements)

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“…In addition, there was disparity in the burden of podoconiosis by gender where prevalence was higher among women (3.7%) than men (2.4%) [ 51 ]. Leg lymphedema has a significant negative socio-economic impact on people affected by podoconiosis and LF and their caregivers in co-endemic districts of Ethiopia [ 56 ] and also increases mortality [ 55 ].…”

Section: Resultsmentioning

confidence: 99%

Burden of neglected tropical diseases and access to medicine and diagnostics in Ethiopia: a scoping review

et al. 2023

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Background More than 1.7 billion people are affected by neglected tropical diseases (NTDs) worldwide. Forty percent of the NTD-affected people live in Africa with the poorest, most vulnerable, and hard to reach geographical areas. The NTDs cause significant social and economic burden and deepen marginalization and stigmatization. The World Health Organization’s current roadmap for NTD aims to prevent, control, eliminate, or eradicate 20 tropical diseases. Ethiopia experiences a high burden of these diseases, but current access to diagnostics, medicine, and/or care has been little explored to inform the country’s NTD strategic plan. The overall purpose of the scoping review was to map and characterize the burden of NTDs and challenges in access to diagnostics, medicine, and/or care in Ethiopia. Methods A systematic search of evidence was conducted in PubMed, Cochrane Library, and Google Scholar from January 2000 until May 2022, without restrictions of language or study design. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Review was followed for screening of studies. Key findings were extracted and narrated qualitatively. Results The search resulted in 4532 articles, of which 105 met the inclusion criteria and were included in the scoping review under three themes: burden of NTDs, access to diagnostics, medicine and/or care, and key barriers. Although gains have been made in the prevention and control of NTDs in Ethiopia, the burden remains high, and progress in access to diagnostics, medicine/drugs, and/or care is very slow. Poverty, poor quality of life, and underfunding of NTD programs decelerate the process of NTD elimination program in the country. Conclusions The scoping review identified a considerable number of studies on the burden of NTDs in Ethiopia and strategies for diagnosis, treatment, and/or care; however, there is a paucity of evidence on the suitability and potential benefits of novel diagnostic technologies and medicines in the country. A regular review and analysis of such country-level evidence is important to inform the country NTDs roadmap and local implementation strategies.

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Section: Resultsmentioning

confidence: 99%

Burden of neglected tropical diseases and access to medicine and diagnostics in Ethiopia: a scoping review

et al. 2023

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“…Both podoconiosis and LF are among the prioritized NTDs in Ethiopia (9). Thirteen relevant articles were identi ed (9,34,54,55,36,(47)(48)(49)(50)(51)(52)(53), that report the burden of podoconiosis or LF in Ethiopia (34,51,52). The burden of podoconiosis ranged from 0.1-8.1%, and cases of podoconiosis are widespread in Africa, where Ethiopia registered the second highest prevalence rate (7.5%), next to Cameroon (8.1%) (9,36,37,47,49).…”

Section: Podoconiosis and Lymphatic Lariasis (Lf)mentioning

confidence: 99%

“…In addition, there was disparity in the burden of podoconiosis by gender where prevalence was higher among women (3.7%) than men (2.4%) (50). Leg lymphoedema has a signi cant negative socio-economic impact on people affected by podoconiosis and LF and their caregivers in coendemic districts of Ethiopia (55), and also increases mortality (54).…”

Section: Podoconiosis and Lymphatic Lariasis (Lf)mentioning

confidence: 99%

Burden of neglected tropical diseases and access to medicine and diagnostics in Ethiopia: A scoping review

Semahegn

Manyazewal

Getachew

et al. 2022

Preprint

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Background The World Health Organization’s new roadmap for neglected tropical diseases (NTDs) 2021–2030 aims to prevent, control, eliminate or eradicate 20 tropical diseases that are affecting the lives of 1.5 billion people worldwide. Ethiopia experiences a high burden of these diseases, but current access to diagnostics, medicine and /or care has been little explored to inform the country’s NTD strategic plan. This scoping review aimed to map and characterize the burden of NTDs and challenges in access to diagnostics, medicine and /or care in Ethiopia. Methods A systematic search was conducted in PubMed, Cochrane Library, and Google Scholar from January 2000 until May 2022 and without restrictions of language or study design. The Preferred Reporting Items for Systematic Reviews and Meta-Analysis Extension for Scoping Review (PRISMA-ScR) was followed and the findings were synthesized narratively. Results The search resulted in 4,532 articles, of which 105 met the inclusion criteria and were included in the scoping review under three themes: burden of NTDs, access to medicine/drug, care and diagnostics. Although gains have been made in the prevention and control of NTDs in Ethiopia, the burden remains high and progress in access to diagnostics, medicine/drugs, and/or care is very slow. Poverty, poor quality of life, and underfunding of NTD programs decelerate the process of NTD elimination program in the country. Conclusions The review identified a considerable number of studies on the burden of NTDs in Ethiopia and strategies for diagnosis, treatment and/or care; however, there is a paucity of evidence on the suitability and potential benefits of novel diagnostic technologies and medicines in the country. A regular review and analysis of such country-level evidence is important to inform the country NTDs roadmap and local implementation strategies.

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“…It is one of the most disabling tropical diseases and reduces productivity, causes stigma from the community and healthcare professionals, and affected people report low quality of life. Although it was thought of as disabling rather than a direct cause of excess mortality, a recent study in Ethiopia demonstrated that people with podoconiosis experience greater mortality than those without podoconiosis in similar community settings (10). The treatment interventions recommended by WHO are commonly known as morbidity management and disability prevention (MMDP) or disease management, disability and inclusion (DMDI).…”

Section: Introductionmentioning

confidence: 99%

Understanding the caring network of podoconiosis patients in Rwanda: a qualitative study

Risat,

Davey,

Mugume

et al. 2024

Front. Trop. Dis

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IntroductionGlobally, a total of almost 4 million people live with podoconiosis in 32 potentially endemic countries including Rwanda. Podoconiosis is a non-infectious geochemical disease that causes massive swelling of the lower leg and is caused by long-term exposure to red clay soil found in tropical highland areas. The disease is a disabling neglected tropical disease (NTD) and is associated with profound stigma, discrimination and comorbid mental health conditions. Treatment interventions are commonly known as morbidity management and disability prevention. Both biomedical and traditional treatments are used by affected people. However, understandings informed by the social sciences of care in the context of NTDs are largely unexplored. This study explored the perspectives and experiences of care among care receivers (podoconiosis patients) and caregivers (family members, traditional healers) in the district of Huye, Rwanda.MethodThe study used qualitative methods including seventeen InDepth Interviews (eleven patients, two traditional healers, two care professionals, and two family members) and participant observation in a health centre and patients’ houses.ResultA caring network was found amongst the podoconiosis patients, their family members, care professionals and traditional healers. Caring network is not only about the medical treatments, but also about the caring relationship amongst them.DiscussionUsing notions of ‘Network’ and ‘Collectives’, from the care ethics literature the study shows that in addition to care work requiring professional know-how, it is also about the relationships between patients, their families, traditional healers, and biomedical care professionals.

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Excess mortality among people with podoconiosis: secondary analysis of two Ethiopian cohorts

Cited by 6 publications

References 4 publications

Burden of neglected tropical diseases and access to medicine and diagnostics in Ethiopia: a scoping review

Burden of neglected tropical diseases and access to medicine and diagnostics in Ethiopia: a scoping review

Burden of neglected tropical diseases and access to medicine and diagnostics in Ethiopia: A scoping review

Understanding the caring network of podoconiosis patients in Rwanda: a qualitative study

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