Excerpts From the US Renal Data System 2009 Annual Data Report

Collins, Allan J.; Foley, Robert N.; Herzog, Charles A.; Chavers, Blanche M.; Gilbertson, David T.; Ishani, Areef; Kasiske, Bertram L.; Liu, Jiannong; Mau, Lih Wen; McBean, Marshall; Murray, Anne M.; Peter, Wendy L. St.; Guo, Haifeng; Li, Qi; Li, Shuling; Li, Suying; Peng, Yen‐Chun; Qiu, Yang; Roberts, Tricia; Skeans, M. A.; Snyder, Jon J.; Solid, Craig A.; Wang, Changchun; Weinhandl, Eric D.; Zaun, David; Arko, Cheryl; Chen, Shu‐Cheng; Dalleska, Frederick; Daniels, Frank; Dunning, Stephan; Ebben, James; Frazier, Eric; Hanzlik, Christopher; Johnson, Roger N.; Sheets, Daniel; Wang, Xinyue; Forrest, Beth; Constantini, Edward; Everson, Susan; Eggers, Paul W.; Agodoa, Lawrence Y.

doi:10.1053/j.ajkd.2009.10.009

Cited by 406 publications

(386 citation statements)

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“…We also found that shorter dialysis vintage and current smoking were risk factors for bacteremia. Previous research indicated that the survival rate of incident dialysis patients was lowest during the first year of treatment (1). Patients with a shorter duration of dialysis may have unstable physical conditions and therefore be more susceptible to bacteremia.…”

Section: Discussionmentioning

confidence: 99%

“…Infection is the second most common cause of mortality and is a major cause of morbidity in dialysis patients from the United States (1). In addition, the annual mortality secondary to sepsis is approximately 100-to 300-fold higher in dialysis patients than in the general United States population (2).…”

Section: Introductionmentioning

confidence: 99%

“…Dialysis patients appear to be predisposed to infection due to alterations in primary host defense, advanced age, and the presence of comorbid conditions such as diabetes mellitus (DM), malnutrition, invasive dialysis procedures, disruption of skin and mucosa barriers, and susceptibility to nosocomial transmis-sion (4,5). Peritonitis, vascular access infection, bacteremia, pneumonia, and cellulitis are the most common types of infections in dialysis patients (1).…”

Section: Introductionmentioning

confidence: 99%

“…A review of the US Renal Data System (USRDS) indicated that first year hospital admission rates for bacteremia were higher for hemodialysis (HD) patients than for peritoneal dialysis (PD) patients (1,6). However, a recent study of a single dialysis center in the US indicated that the overall infection rate in incident dialysis patients was similar for patients undergoing HD and PD, but that HD patients had a higher risk of bacteremia and PD patients had a higher risk of peritonitis (7).…”

Section: Introductionmentioning

confidence: 99%

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Bacteremia in Hemodialysis and Peritoneal Dialysis Patients

et al. 2012

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Objective To analyze the incidence rates and risk factors for bacteremia in patients undergoing hemodialysis (HD) and peritoneal dialysis (PD). Methods The records of 898 consecutive patients undergoing dialysis from January 2003 to December 2008 were reviewed retrospectively. Episodes of bacteremia were recorded. China Medical University (Taichung, Taiwan). Results The overall incidence rate of bacteremia was 7.63 per 100 patient-years in HD patients and 3.56 per 100 patient-years in PD patients and it was higher in HD patients each year from 2003 to 2008. S. aureus (27.53%) was the most common pathogen in HD patients, whereas Coagulase-negative Staphylococcus (21.3%) was the most common pathogen in PD patients. Vascular access infection was the most common etiology in HD patients, whereas peritonitis was the most common etiology in PD patients. Older age, shorter dialysis vintage, use of HD rather than PD, current smoker, use of a venous dialysis catheter, presence of diabetes mellitus, higher comorbidity score, and lower serum albumin were significant risk factors for bacteremia. Diabetes mellitus and lower serum albumin were significant risk factors for bacteremia-associated mortality. Conclusion Placement of a permanent access (fistula, graft, or PD catheter) prior to initiation of dialysis, smoking cessation, and better nutritional status (i.e. higher serum albumin) were associated with a reduced risk of bacteremia in dialysis patients. Higher serum albumin was also associated with a reduced bacteremiaassociated mortality.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Bacteremia in Hemodialysis and Peritoneal Dialysis Patients

et al. 2012

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“…[25] The risk of cardiovascular mortality is more than 10 times higher in this population compared with an age, sex, and race matched population. [26] Data on cardiovascular risk factors from the general population cannot simply be extrapolated to CKD patients as they are subject not only to traditional risk factors, but also to CKD-related risk factors such as inflammation, increased calcium and phosphorus products, uremic toxins, anemia, and fluid overload.…”

Section: Introductionmentioning

confidence: 80%

Pattern and severity of left ventricular diastolic dysfunction in early and end stage renal disease patients with or without dialysis in rural population in South India

Sidmal¹,

Hp²,

Kc³

2015

Int Jour of Biomed Res

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Background: The chronic kidney disease (CKD) is a major risk factor for coronary artery disease (CAD) and left ventricle systolic dysfunction. Left ventricular (LV) diastolic dysfunction in CKD patients frequently leads to the development of congestive heart failure. The interaction between diastolic dysfunction (DD) and renal function in subjects with preserved systolic function is not well defined. Objective: Our aim was to investigate whether renal insufficiency (RI) is associated with DD among patients with left ventricular ejection fraction (LVEF) > 50%, and to investigate whether there is a correlation between CKD and DD severity. Methods: Eighty four CKD patients, aged 35-79 were examined by standard echocardiography. Subjects were divided into 4 groups depending on their estimated glomerular filtration rate (eGFR: ml/min/BSA) as follows: group 1 (60-89 ml/min/BSA), group 2 (30-59 ml/min/BSA), group 3 (15-29 ml/min/BSA) and group 4 (less than 15 ml/min/BSA), between 1/2/2014 and 30/4/2015. Glomerular filtration rate (GFR) was estimated using the MDRD formula. Patients with impaired relaxation (grade I) were compared to those with pseudonormal (grade II) or restrictive (grade III-IV) DD. Results: Among 84 patients, 23 had GFR 60-89 ml/min/BSA; 16 had GFR 30-59 ml/min/BSA; and 19 had GFR 15-30 ml/min/BSA and 26 had GFR <15 ml/min/BSA. There was a significant correlation between worsening GFR and degree of diastolic dysfunction (DD) assessed by echo. Overall, 40.4% of the participants were female, 22 (26.1 %) had grade I, & 10 (11.9 %) had grade II, 16 (19%) had grade III and 36 (42.8%) had grade IV diastolic dysfunction. Almost all patients had some degree of diastolic dysfunction. With worsening of renal function, there was worsening of diastolic dysfunction seen. In patients with end stage renal disease many had grade IV diastolic dysfunction as compared to patients with early CKD. Grade I and II DD was commonly seen in group 1 and 2. But grade III and IV DD was commonly seen in group 3 and 4. Conclusion: Worsening renal function was associated with greater degree of diastolic dysfunction and adverse clinical outcomes. Our Study indicated a clear and independent association between RI and DD. The severity of RI also tends to correlate with the severity of DD. And that LV diastolic dysfunction was observed even in patients with early stages of chronic kidney dysfunction.

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Renoprotective Effect of Renin-Angiotensin-Aldosterone System Blockade in Patients With Predialysis Advanced Chronic Kidney Disease, Hypertension, and Anemia

et al. 2014

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The benefit of using a renin-angiotensin-aldosterone system blocker such as an angiotensin-converting enzyme inhibitor (ACEI) or an angiotensin II receptor blocker (ARB) for patients with advanced chronic kidney disease (CKD) remains undetermined.OBJECTIVE To assess the effectiveness and safety of ACEI/ARB use for advanced predialysis CKD in patients with hypertension and anemia.DESIGN Prospective cohort study. SETTING Taiwan.

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Excerpts From the US Renal Data System 2009 Annual Data Report

Cited by 406 publications

References 0 publications

Bacteremia in Hemodialysis and Peritoneal Dialysis Patients

Bacteremia in Hemodialysis and Peritoneal Dialysis Patients

Pattern and severity of left ventricular diastolic dysfunction in early and end stage renal disease patients with or without dialysis in rural population in South India

Renoprotective Effect of Renin-Angiotensin-Aldosterone System Blockade in Patients With Predialysis Advanced Chronic Kidney Disease, Hypertension, and Anemia

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