Excerpts from the United States Renal Data System 2004 Annual Data Report: Atlas of end-stage renal disease in the United States

Collins, Allan J.; Kasiske, B. L.; Herzog, Charles A.; Chavers, Blanche M.; Foley, Rob; Gilbertson, David T.; Grimm, Richard A.; Liu, Jiannong; Louis, Thomas St.; Manning, W; Matas, Arthur J.; McBean, Marshall; Murray, Anne M.; Peter, Wendy L. St.; Xue, Jay L.; Fan, Qiao; Guo, Haifeng; Li, Shuling; Li, Suying; Roberts, Tricia; Snyder, Jon J.; Solid, Craig A.; Wang, Changchun; Weinhandl, Eric D.; Arko, Cheryl; Chen, Shu‐Cheng; Dalleska, Frederick; Daniels, Frank; Dunning, Stephan; Ebben, James; Frazier, Eric; Johnson, Roger N.; Sheets, Daniel; Forrest, Beth; Berrini, Delaney; Constantini, Edward; Everson, Susan; Frederick, Pamela R.; Eggers, Paul W.; Agodoa, Lawrence

doi:10.1053/j.ajkd.2004.10.009

Cited by 333 publications

(227 citation statements)

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“…The mechanism of elevated zinc after hemodialysis not yet understood, our suggestion could be related to increase transporter protein after hemodialysis, it is well known that zinc transported bound with prealbumin, albumin and transferrin, thus could protected against filtration during hemodialysis, this providing interesting observation that, beside elevated zinc levels after hemodialysis CKD patients have decrease zinc level. In fact that zinc deficiency in developing countries due to socioeconomic and malnutrition factors associated with delayed wound healing (Shrimpton et al, 2005;Prasad, 1988), and immune deficiency which might contribute to the excess risk of infection observed in hemodialysis patients (Collins et al 2005;Ishani et al, 2005;Rink and Gabriel, 2000).…”

Section: Resultsmentioning

confidence: 99%

Impact of Hemodialysis on Serum Zinc and Copper Level in CKD Patients

Balla¹,

Adam²

2016

J App Pharm Sci

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The aim of this study was to assess the effect of HD on zinc and copper level among CKD patients. A crosssectional study included 40 subjects (15 female and 25 male) from academic hospital aged (22-80 years old) were included, timed pre and post-hemodialysis samples were collected. Serum zinc, copper, urea and creatinine were measured by using atomic absorption spectroscopy 210-VGP ® and Mindray Bs-200 respectively, and BMI was estimated. Paired t-test analyses showed significant decrease in mean copper, urea and creatinine with p-value (0.025, 0.000 and 0.000) respectively, while significant increase was observed in zinc level p-value 0.035. Person's correlation showed positive correlation between change in zinc level and reduction in urea, and no correlation noted between change in serum copper level and reduction in urea and creatinine. In conclusion HD decrease copper and increase zinc as both are antagonists, might play a vital role in pathogenesis of related disorders in CKD Patients.

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Section: Resultsmentioning

confidence: 99%

Impact of Hemodialysis on Serum Zinc and Copper Level in CKD Patients

Balla¹,

Adam²

2016

J App Pharm Sci

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“…Zinc deficiency is a leading cause of disease in developing countries (5), and is associated with delayed wound healing (14), and immune deficiency characterized by impaired cell proliferation, abnormal T-cell function, defective phagocytosis, and abnormal cytokine expression (15,16), all of which might contribute to the excess risk of infection observed in hemodialysis patients (17). Zinc deficiency may also cause or contribute to a number of relatively non-specific conditions commonly observed in hemodialysis patients, including anorexia, dysgeusia, and impaired cognitive function (18,19).…”

Section: Discussionmentioning

confidence: 99%

Effect of Hemodialysis on Serum Copper and Zinc Levels in Renal Failure Patients

2013

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“…The number of the patients with end-stage renal disease is growing worldwide [3][4][5][6] . It is urgent to establish a new cure for glomerular diseases.…”

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confidence: 99%