Objective
The purpose of this study was to quantify risk of stroke following chiropractic spinal manipulation, as compared to evaluation by a primary care physician, for Medicare beneficiaries aged 66–99 years with neck pain.
Methods
This is a retrospective cohort analysis of a 100% sample of annualized Medicare claims data on 1,157,475 beneficiaries aged 66–99 years with an office visit to either a chiropractor or primary care physician for neck pain. We compared hazard of vertebrobasilar stroke and any stroke at 7 and 30 days following office visit using a Cox proportional hazards model. We used direct adjusted survival curves to estimate cumulative probability of stroke up to 30 days for the two cohorts.
Results
The proportion of subjects with stroke of any type in the chiropractic cohort was 1.2 per 1,000 at 7 days, and 5.1 per 1,000 at 30 days. In the primary care cohort, the proportion of subjects with stroke of any type was 1.4 per 1,000 at 7 days, and 2.8 per 1,000 at 30 days. In the chiropractic cohort, the adjusted risk of stroke was significantly lower at 7 days as compared to the primary care cohort (hazard ratio 0.39; 95% CI 0.33–0.45), but at 30 days, a slight elevation in risk was observed for the chiropractic cohort (hazard ratio 1.10; 95% CI 1.01–1.19).
Conclusions
Among Medicare B beneficiaries aged 66–99 with neck pain, incidence of vertebrobasilar stroke was extremely low. Small differences in risk between patients who saw a chiropractor and those who saw a primary care physician are probably not clinically significant.