:In the path-finding activities, people need to rely on two environmental designs, one is the environment itself -the sight towards the destination, the reference object to help maintain the correct direction, and the intuitive judgment of the exit location. The second is signs, guide signs, markings and other auxiliary tools, which complement and explain the environment itself as a positive factor. The closed characteristics of expressway and the complex and three-dimensional development of road network make the driving environment of the highway itself not distinctive, the visual accessibility is low, the spatial information is difficult to obtain from a macro perspective, and it is easy to get lost, so it is very dependent on guidance facilities such as guide signs, maps, navigation, etc. Give full play to the management and service functions of road traffic signs and markings, so as to prevent and reduce traffic accidents, ensure driving safety, and make road users feel comfortable and happy. Summarize the research on the setting of the guide signs of the expressway hub interchange, and clarify its development context and current research direction.