Examining Parental Medication Adherence as a Predictor of Child Medication Adherence in Pediatric Anxiety Disorders

Bushnell, Greta A.; Brookhart, M. Alan; Compton, Scott N.; Dusetzina, Stacie B.; Stürmer, Til

doi:10.1097/mlr.0000000000000911

Cited by 7 publications

(14 citation statements)

References 57 publications

(62 reference statements)

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“…In the latter situation, a parent's mental health condition could lead to the recognition of the importance of outpatient treatment. 54 Findings reported by Jon-Ubabuco & Dimmitt Champion 66 and Bushnell et al 72 corroborate that hypothesis. The first study found that African American caregivers who struggled with mental health issues themselves were better able to recognize these issues in adolescents and were more predisposed to seek out MHS.…”

Section: Discussionmentioning

confidence: 59%

“…Bushnell et al expanded the scope of the issue to how parents understood their overall health (by assessing their adherence to statin and antihypertension medication use) and the effect this had on adherence to their children's anxiety treatment, concluding that perceptions of the parent's own health and need for treatment could be an important predictor of child and adolescent treatment compliance overall. 72 Interventions occurring in EDs 42,50,53 and in initial inpatient treatment 25,51 were shown to improve treatment compliance. Several other studies have addressed the effects of ED interventions on the treatment compliance of adolescents and young people with SB.…”

Section: Discussionmentioning

confidence: 99%

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Treatment compliance and risk and protective factors for suicide ideation to completed suicide in adolescents: a systematic review

Rufino

Fidalgo

Santos

et al. 2021

Braz. J. Psychiatry

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Objective: To review the literature regarding adolescent suicide risk and explore the associations between treatment compliance (expressed as a concept including measured adherence to treatment and/or mental health service utilization) and risk and protective factors for suicidal behavior (SB), as well as the association between treatment compliance and reattempts. Methods: PubMed, LILACS, and Google Scholar were searched using the following terms: (adolescent*) AND (suicide*) AND (risk factor OR protective factors) AND (treatment compliance OR treatment attrition OR treatment adherence OR treatment drop out OR treatment retention OR mental health utilization). We retrieved studies that focused on the relation of treatment compliance to risk and protective factors for SB and that had only adolescent samples. Results: Of 4,841 articles, 30 original articles were selected for review. Most studies indicated high mental health service (MHS) utilization and poor treatment adherence by SB patients. Social minority status and conduct disorder were associated with less treatment adherence, while female sex, parental perceived need for treatment, and major depression were associated with greater treatment adherence. Inpatient and intensive emergency care after SA and family interventions improved MHS utilization and treatment compliance. However, we found no substantial protective effect of treatment compliance against reattempts. Conclusion: Effective treatment planning for compliance requires considering psychopathology, treatment planning, and social, familial, and individual factors.

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Section: Discussionmentioning

confidence: 59%

Section: Discussionmentioning

confidence: 99%

Treatment compliance and risk and protective factors for suicide ideation to completed suicide in adolescents: a systematic review

Rufino

Fidalgo

Santos

et al. 2021

Braz. J. Psychiatry

View full text Add to dashboard Cite

show abstract

“…However, a study among children with anxiety disorders documented that treatment adherence was associated with the length of medication usage. 33 Possible reasons for a decline in the compliance with medication over a longer time period could be the lack of continuous or regular health education support.…”

Section: Compliance With Medicationmentioning

confidence: 99%

“…A review of studies on compliance with medication in children with epilepsy identified several environment-related factors influencing compliance with medication. 33,34 For example, three identified studies in the review documented that Score range of the multiple-choice questions was 0-2 support form medical and nursing staff was related to better adherence. Three other studies reported that better socio-economic status of the family would predict better compliance with medication.…”

Section: Compliance With Medicationmentioning

confidence: 99%

“…General strategies to improve compliance with medication can be related to family members but should also include healthcare professionals. 30,33 For parents, support strategies could include education or counselling, information brochures, and reminders. Healthcare professionals need to consider to organise continuous education on compliance with medication, build a stronger child-professional relationship, or develop multidisciplinary teams with specific roles in follow-up clinics.…”

Section: Implication For Clinical Practicementioning

confidence: 99%

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Compliance with aspirin in paediatric CHD post-percutaneous transcatheter occlusion: a cross-sectional study

et al. 2020

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Background: Predictors of compliance with aspirin in children following cardiac catheterisation have not been identified. The aim of this study is to identify the caregivers’ knowledge, compliance with aspirin medication, and predictors of compliance with aspirin in children with Congenital Heart Disease (CHD) post-percutaneous transcatheter occlusion. Methods: A cross-sectional explorative design was adopted using a self-administered questionnaire and conducted between May 2017 and May 2018. Recruited were 220 caregivers of children with CHD post-percutaneous transcatheter occlusion. Questionnaires included child and caregivers’ characteristics, a self-designed and tested knowledge about aspirin scale (scoring scale 0–2), and the 8-item Morisky Medication Adherence Scale (scoring scale 0–8). Data were analysed using multivariate binary logistic regression analysis to identify predictors of compliance with aspirin. Results: Of the 220 eligible children and caregivers, 210 (95.5%) responded and 209 surveys were included in the analysis. The mean score of knowledge was 7.25 (standard deviation 2.27). The mean score of compliance was 5.65 (standard deviation 1.36). Child’s age, length of aspirin use, health insurance policies, relationship to child, monthly income, and knowledge about aspirin of caregivers were independent predictors of compliance with aspirin (p < 0.05). Conclusion: Caregivers of children with CHD had an adequate level of knowledge about aspirin. Compliance to aspirin medication reported by caregivers was low. Predictors of medium to high compliance with aspirin were related to the child’s age and socio-economic reasons. Further studies are needed to identify effective strategies to improve knowledge, compliance with medication, and long-term outcomes of children with CHD.

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Costs of Prescription Drugs for Children and Parental Adherence to Long-Term Medications

Lauffenburger,

Barlev,

Olatunji

et al. 2023

JAMA Netw Open

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ImportanceThe adverse effects of prescription drug costs on medication adherence and health have been well described for individuals. Because many families share financial resources, high medication costs for one could lead to cost-related nonadherence in another; however, these family-level spillover effects have not been explored.ObjectiveTo evaluate whether the cost of a child’s newly initiated medication was associated with changes in their parent’s adherence to their own medications and whether that differed by likely duration of treatment.Design, Setting, and ParticipantsThis cohort study used interrupted time-series analysis with a propensity score-matched control group from a large national US health insurer database (2010-2020) and included children initiating medication and their linked presumed parents using long-term medications.ExposureThe cost of the child’s initiated medication. Child medication cost was classified based on highest (≥90th) or lowest (&lt;10th) decile from out-of-pocket medication spending, stratified by whether the medication was intended for short- or long-term use. Children initiating high-cost medications (based on the highest decile) were propensity-score matched with children initiating low-cost medications.Main Outcome and MeasuresThe child’s parent’s adherence to long-term medication assessed by the widely used proportion of days covered metric in 30-day increments before and after the child’s first fill date. Parent demographic characteristics, baseline adherence, and length of treatment, and family unit size and out-of-pocket medication spending were key subgroups.ResultsAcross 47 154 included pairs, the parents’ mean (SD) age was 42.8 (7.7) years. Compared with a low-cost medication, initiating a high-cost, long-term medication was associated with an immediate 1.9% (95% CI, −3.8% to −0.9%) reduction in parental adherence sustained over time (0.2%; 95% CI, −0.1% to 0.4%). Similar results were observed for short-term medications (0.6% immediate change; 95% CI, −1.3% to −0.01%). Previously adherent parents, parents using treatment for longer periods, and families who spent more out-of-pocket on medications were more sensitive to high costs, with immediate adherence reductions of 2.8% (95% CI, −4.9% to −0.6%), 2.7% (95% CI, −4.7% to −0.7%), and −3.8% (95% CI, −7.2% to −0.5%), respectively, after long-term medication initiation.Conclusions and RelevanceIn this cohort study small reductions in adherence across parents with higher child drug costs were observed. Health care systems should consider child-level or even household-level spending in adherence interventions or prescription policy design.

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Examining Parental Medication Adherence as a Predictor of Child Medication Adherence in Pediatric Anxiety Disorders

Abstract: Parental medication adherence could help providers identify children at risk of nonadherence to inform the treatment decision, reduce unnecessary medication switches, and lead to broader effective interventions.

Cited by 7 publications

References 57 publications

Treatment compliance and risk and protective factors for suicide ideation to completed suicide in adolescents: a systematic review

Treatment compliance and risk and protective factors for suicide ideation to completed suicide in adolescents: a systematic review

Compliance with aspirin in paediatric CHD post-percutaneous transcatheter occlusion: a cross-sectional study

Costs of Prescription Drugs for Children and Parental Adherence to Long-Term Medications

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