Examination of Gland Dropout Detected on Infrared Meibography by Using Optical Coherence Tomography Meibography

Yoo, Young-Sik; Na, Kyung‐Sun; Byun, Yong-Soo; Shin, Jun Geun; Lee, Byeong Ha; Yoon, Geunyoung; Eom, Tae Joong; Joo, Choun‐Ki

doi:10.1016/j.jtos.2016.10.001

Cited by 35 publications

(22 citation statements)

References 38 publications

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“…Traditionally, the structural details of the glands have been evaluated by biopsy or contact meibography, the former being clearly a drastically more invasive technique than the latter [82]. In recent years, OCT imaging of glandular tissue has been shown to be effective, leading to the growing diffusion of this contactless, in vivo, direct, reliable and patient-friendly technique [83][84][85][86]. Several authors have confirmed that meibomian glands can be optimally visualized using commercial OCTs and custom-built systems.…”

Section: Meibomian Glandsmentioning

confidence: 99%

Fourier-Domain OCT Imaging of the Ocular Surface and Tear Film Dynamics: A Review of the State of the Art and an Integrative Model of the Tear Behavior during the Inter-Blink Period and Visual Fixation

Napoli

Nioi

Mangoni

et al. 2020

JCM

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In the last few decades, the ocular surface and the tear film have been noninvasively investigated in vivo, in a three-dimensional, high resolution, and real-time mode, by optical coherence tomography (OCT). Recently, OCT technology has made great strides in improving the acquisition speed and image resolution, thus increasing its impact in daily clinical practice and in the research setting. All these results have been achieved because of a transition from traditional time-domain (TD) to Fourier-domain (FD) technology. FD-OCT devices include a spectrometer in the receiver that analyzes the spectrum of reflected light on the retina or ocular surface and transforms it into information about the depth of the structures according to the Fourier principle. In this review, we summarize and provide the state-of-the-art in FD-OCT imaging of the ocular surface system, addressing specific aspects such as tear film dynamics and epithelial changes under physiologic and pathologic conditions. A theory on the dynamic nature of the tear film has been developed to explain the variations within the individual compartments. Moreover, an integrative model of tear film behavior during the inter-blink period and visual fixation is proposed.

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Section: Meibomian Glandsmentioning

confidence: 99%

Fourier-Domain OCT Imaging of the Ocular Surface and Tear Film Dynamics: A Review of the State of the Art and an Integrative Model of the Tear Behavior during the Inter-Blink Period and Visual Fixation

Napoli

Nioi

Mangoni

et al. 2020

JCM

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“…To overcome these challenges, three-dimensional meibomian gland imaging can be obtained via SSOCT. OCT can provide detailed images of the meibomian gland acini and ducts not seen on infrared imaging; however, the correlation between acinar morphological changes (constricted, atrophic, absent) was not well correlated with meibomian gland dropout 37. OCT meibography demonstrated that in obstructive MGD there is a decrease in meibomian gland length and width compared with the control, which are correlated with OSDI score and TFBUT, respectively; however, no differences in the number and diameter of meibomian gland orifices were found between the two groups 38.…”

Section: Imaging Techniquesmentioning

confidence: 97%

Advances in dry eye imaging: the present and beyond

et al. 2017

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New advances in imaging allow objective measurements for dry eye as well as define new parameters that cannot be measured by clinical assessment alone. A combination of these modalities provides unprecedented information on the static and dynamic properties of the structural and functional parameters in this multifactorial disease. A literature search was conducted to include studies investigating the use of imaging techniques in dry eye disease. This review describes the application of non-invasive tear breakup time, optical coherence tomography, meibomian gland imaging, interferometry, in vivo confocal microscopy, thermography and optical quality assessment for this condition.

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“…Оптическая когерентная томография (ОКТ). Кроме возможности изучения параметров слезного мениска, описанных выше, применение ОКТ позволило получить объемные 2D-и 3D-томограммы мейбомиевых желез в естественных условиях (гипертрофия или атрофия мейбомиевых желез) [48,49]. Недоказанным является преимущество этого метода перед другими методами визуализации, так как из-за рассеяния и поглощения света биологической тканью глубина сканирования при ОКТ ограничена.…”

Section: инструментальные исследованияunclassified

Modern methods of evaluating the morphological and functional state of the eyelids in chronic blepharitis

et al. 2018

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В обзоре литературы представлены современные методы исследования морфофункционального состояния век при хроническом блефарите, разработка которых связана с продолжающимся изучением этиологии и патогенеза заболевания. Ключевые слова: блефарит, лазерная допплеровская флоуметрия, лазерная сканирующая конфокальная микроскопия, инфракрасная мейбография.

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Examination of Gland Dropout Detected on Infrared Meibography by Using Optical Coherence Tomography Meibography

Cited by 35 publications

References 38 publications

Fourier-Domain OCT Imaging of the Ocular Surface and Tear Film Dynamics: A Review of the State of the Art and an Integrative Model of the Tear Behavior during the Inter-Blink Period and Visual Fixation

Fourier-Domain OCT Imaging of the Ocular Surface and Tear Film Dynamics: A Review of the State of the Art and an Integrative Model of the Tear Behavior during the Inter-Blink Period and Visual Fixation

Advances in dry eye imaging: the present and beyond

Modern methods of evaluating the morphological and functional state of the eyelids in chronic blepharitis

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