Examination of 2-methacryloyloxyethyl phosphorylcholine polymer coated acrylic resin denture base material: surface characteristics and Candida albicans adhesion

Türkcan, İrem; Nalbant, Ahmet; Bat, Erhan; Akca, Gülçin

doi:10.1007/s10856-018-6116-7

Cited by 16 publications

(14 citation statements)

References 55 publications

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“…16 This is assured by the correlation results of our study, which demonstrate a significant positive correlation between SR and candida adhesion. In contrast to this result, a previous study 39 found a slight rise in surface roughness values parallel to the increase in MPC polymer ratios.…”

Section: Discussioncontrasting

confidence: 98%

“…Therefore, polyamide surface modification with MPC in a monomer density of 0.75 mol/L is suggested to be efficient, as it recorded decreased surface roughness and candida adhesion. While a previous study 39 recommended the MPC modification with 0.5 mol/ L concentration for coating acrylic denture base which recorded low candida adhesion with slight increase in surface roughness. This result can be explained by the difference in composition of both denture base materials.…”

Section: Discussionmentioning

confidence: 92%

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Evaluation of 2-methacryloyloxyethyl phosphorylcholine polymer coated polyamide denture base material: Surface Roughness and Candida Albicans adhesion.

Maaly

Mohamed

2021

Egyptian Dental Journal

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Purpose: To evaluate surface roughness and Candida albicans adhesion of polyamide resin denture base coated with various concentrations of MPC polymer, 2-methacryloyloxyethyl phosphorylcholine. Materials and Methods:A total of eighty polyamide disks were prepared and divided into four groups (n = 20/group). Surfaces of specimens in three groups were treated with MPC in various concentrations (0.25 mol/L; 0.50 mol/L and 0.75 mol/L), whereas uncoated specimens were used as control. Surface roughness (SR) was evaluated using a profilometer. Incubation of the specimens with C. albicans was done overnight, and the count of adhered cells was estimated. Statistically, the following tests were done: analysis of variance, Pearson correlation coefficient test, post hoc Tukey test.Results: Upon PMPC coating, surface roughness values were decreased, with a significant difference between the groups. There was significant decrease in C. albicans count with the increase in the MPC polymer concentration. For the modified groups, 0.50 mol/L and 0.75 mol/L, showed no significant difference for candida adhesion while significantly different for surface roughness. These results showed that polymerization of MPC by graft method on polyamide denture base material decreases the attachment of C. albicans, consequently, it is recommended as a coating for elimination of denture stomatitis.Conclusion: modification of polyamide prosthesis with 0.75 mol/L MPC is suitable to diminish C. albicans adhesion on the denture base and a decreasing effect on the surface roughness values.

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Section: Discussioncontrasting

confidence: 98%

Section: Discussionmentioning

confidence: 92%

Evaluation of 2-methacryloyloxyethyl phosphorylcholine polymer coated polyamide denture base material: Surface Roughness and Candida Albicans adhesion.

Maaly

Mohamed

2021

Egyptian Dental Journal

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“…Wettability was measured in accordance with the methods of previous studies [19,20]. Glycerol solution was chosen as the reference liquid, since it is an ideal blood analog with a similar viscosity to the normal range of human blood [19,21].…”

Section: Methodsmentioning

confidence: 99%

Novel anti-biofouling bioactive calcium silicate-based cement containing 2-methacryloyloxyethyl phosphorylcholine

et al. 2019

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Calcium silicate-based cements (CSCs) are commonly used for endodontic procedures; however, their antibacterial effects are limited. The objective of this study was to develop a 2-methacryloyloxyethyl phosphorylcholine (MPC)-incorporated CSC with improved antibacterial properties, while maintaining the original advantageous features of CSC. MPC was incorporated into a commercial CSC (Endocem MTA) at 0 wt% (control), 1.5%, 3.0 wt%, 5.0 wt%, 7.5 wt%, and 10 wt%. The setting time, compressive strength, water sorption, and glycerol contact angle were measured. Protein absorption was measured and bacterial adhesion on the surface was evaluated using Enterococcus faecalis. The bactericidal effect was examined by the disc diffusion test. Mineralization ability was assessed based on calcium ion deposition, as assessed by alizarin red staining, after immersion into Hank’s balanced salt solution for 7 days. High concentrations of MPC in CSC (7.5 wt% and 10 wt%) increased the setting time, reduced compressive strength, and reduced wettability. MPC (3 wt%) had greater protein repellent and anti-biofouling effects than those of control and test materials (P < 0.001). However, no bactericidal effect was observed for any control or test materials. There was greater calcium ion deposition on the surface of MPC-supplemented CSC than on the control (P < 0.001). The addition of 3 wt% MPC polymer to CSC confers protein-repellent properties and reduced bacterial attachment, with the potential for improved mineralization.

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“…Applying the inclusion criteria, out of the 21 included articles,[ 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 ] 16 used surface coating, 4 added antimicrobial fillers, and 1 modified the chemical composition of PMMA (refer to Tables 2 and 3 for details). In addition to that, several included studies compared between smooth and rough surfaces of the modified specimens.…”

Section: R Esultsmentioning

confidence: 99%

Hydrophobicity of Denture Base Resins

Gad

Abualsaud

Khan

2022

Journal of International Society of Preventive and Community Dentistry

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A BSTRACT Objectives: The aim of this article is to review the factors that attract Candida albicans to denture base resin (DBR) and to verify the influence of different surface treatments, chemical modification, or structural reinforcements on the properties of DBR. Materials and Methods: Searches were carried out in PubMed, Scopus, WOS, Google Scholar, EMBASE, and J-stage databases. The search included articles between 1999 and 2020. This study followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement. The keywords used during the search were “ Candida albicans ,” “Denture base,” “PMMA,” “Acrylic resin,” “Surface properties,” “hydrophobicity/hydrophilicity,” “contact angle,” and “surface free energy.” English full-text articles involving in-vitro studies with different acrylic resin modifications were included, whereas abstracts, dissertations, reviews, and articles in languages other than English were excluded. A meta-analysis was performed where appropriate. Results: Out of the 287 articles, 21 articles conformed to inclusion criteria. Sixteen articles were subjected to meta-analysis using random-effects model at 95% confidence interval. Results showed that DBR coatings/plasma coatings were effective methods to modify surface properties with estimated contact angle (CA) of 59.37° [95% confidence interval (CI): 53.69, 65.04]/55.87° (95% CI: 50.68, 61.06) and surface roughness ( R a ) of 0.55 µm (95% CI: 0.52, 0.58)/0.549 µm (95% CI: 0.5, 0.59), respectively. Antifungal particle incorporation into poly(methylmethacrylate) DBR also produced similar effects with an estimated R a of 0.16 µm (95% CI: 0.134, 0.187). Conclusion: The three properties responsible for C. albicans adhesion to DBR were R a , CA, and surface free energy in terms of hydrophobicity. Therefore, the correlations between the hydrophobicity of DBR and C. albicans adhesion should be considered during future investigations for Candida -related denture stomatitis.

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Examination of 2-methacryloyloxyethyl phosphorylcholine polymer coated acrylic resin denture base material: surface characteristics and Candida albicans adhesion

Cited by 16 publications

References 55 publications

Evaluation of 2-methacryloyloxyethyl phosphorylcholine polymer coated polyamide denture base material: Surface Roughness and Candida Albicans adhesion.

Evaluation of 2-methacryloyloxyethyl phosphorylcholine polymer coated polyamide denture base material: Surface Roughness and Candida Albicans adhesion.

Novel anti-biofouling bioactive calcium silicate-based cement containing 2-methacryloyloxyethyl phosphorylcholine

Hydrophobicity of Denture Base Resins

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