This paper studies the flexural performance of sandwich panels composed of a soft polyurethane foam core and glass fibre-reinforced polymer (GFRP) skins. A robust analytical model is developed to predict the full load-deflection and strain responses of the panel. It is based on equilibrium and strain compatibility and accounts for the excessive shear deformation and material nonlinearity of the core. It also accounts for geometric nonlinearity in the form of localized deflection of the loaded skin using the principals of beam-on-elastic foundation and the change in core thickness due to its softness. The model incorporates various failure criteria, namely core shear failure, core flexural tension or compression failure, compression skin crushing or wrinkling, or tensile rupture of skin. The model has the advantage of being able to isolate quantitatevely the individual contributions of flexure, shear, and localized skin deformations, to overall deflection. A parametric study is performed to examine the effects of core density and skin thickness on panel behavior. It is shown that as the core density increases from 32 to 192 kg/m 3 , the contribution of shear to overall deflection reduces from about 90 to 10 percent. It also appears that the optimal core density of the sandwich panels is within 96 to 128 kg/m 3 , which represents the lowest density necessary to achieve the highest ultimate strength and stiffness.