2014
DOI: 10.1093/molbev/msu236
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ExaBayes: Massively Parallel Bayesian Tree Inference for the Whole-Genome Era

Abstract: Modern sequencing technology now allows biologists to collect the entirety of molecular evidence for reconstructing evolutionary trees. We introduce a novel, user-friendly software package engineered for conducting state-of-the-art Bayesian tree inferences on data sets of arbitrary size. Our software introduces a nonblocking parallelization of Metropolis-coupled chains, modifications for efficient analyses of data sets comprising thousands of partitions and memory saving techniques. We report on first experien… Show more

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Cited by 407 publications
(321 citation statements)
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References 16 publications
(18 reference statements)
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“…Efficient, highly parallelised algorithms for analysing genomic-scale data do not yet simultaneously infer topology and divergence dates, although some can accommodate morphological data in (undated) simultaneous analyses [68]. Genomic datasets are thus typically analysed stepwise, with topology inferred first, then fixed and time-scaled by node dating [2,3,10].…”
Section: Reviewmentioning
confidence: 99%
“…Efficient, highly parallelised algorithms for analysing genomic-scale data do not yet simultaneously infer topology and divergence dates, although some can accommodate morphological data in (undated) simultaneous analyses [68]. Genomic datasets are thus typically analysed stepwise, with topology inferred first, then fixed and time-scaled by node dating [2,3,10].…”
Section: Reviewmentioning
confidence: 99%
“…We used EXABAYES v. 1.4.1 [52] for Bayesian analysis of the concatenated data matrix, with the GTR ĂŸ G model and the same three partition schemes employed in RAxML. Each EXABAYES analysis included two independent runs, each having four coupled chains, and each run was performed for 500 000 generations, sampling every 100 generations.…”
Section: (D) Phylogenetic Analysesmentioning
confidence: 99%
“…The resulting RaxML bootstrap tree was analysed with RogueNaRok (Aberer et al 2013). The Bayesian inference was performed with ExaBayes 1.5 (Aberer et al 2014) using the GTR substitution model. Four independent runs with each four Monte Carlo Markov Chains were run for 1,000,000 generations during which convergence, with a standard deviation of split frequencies <2%, had been reached.…”
Section: Methodsmentioning
confidence: 99%