Ex-Press® versus Baerveldt implant surgery for primary open-angle glaucoma and pseudo-exfoliation glaucoma

Tojo, Naoki; Hayashi, Atsushi

doi:10.1007/s10792-020-01668-y

Cited by 3 publications

(3 citation statements)

References 17 publications

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“…These results underscore the favorable outcomes associated with the use of the PGI in the management of PXG and POAG patients. The study findings present a notable and somewhat unexpected result, as cases with unsuccessful previous filtration surgery, are generally associated with poor outcomes in subsequent surgeries ( 22 ). Despite this expectation, the PGI group in this study demonstrated successful surgical outcomes, even though it included a significantly higher proportion of patients with a history of filtration surgery.…”

Section: Discussionmentioning

confidence: 74%

Assessing the Efficacy of the PAUL Glaucoma Implant in Pseudoexfoliative Glaucoma

Olgun

2024

Beyoglu Eye J

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Objectives: The aim of the study was to evaluate the outcomes and complications associated with PAUL glaucoma implant (PGI) surgery in pseudoexfoliation glaucoma (PXG) patients, comparing them with a primary open-angle glaucoma (POAG) control group. Methods: A retrospective analysis included 39 PXG and 29 POAG eyes undergoing PGI surgery between January 2020 and December 2022. Surgical success was defined as intraocular pressure (IOP) between ≤21 and ≥6 mmHg at 12 months and no loss of light perception. Demographic data, ocular examinations, and complications were recorded. Results: PXG patients (68.5±9.9 years) differed significantly in age from POAG patients (54.1±10.6 years) (p<0.05). Surgical success rates at 12 months were 97.4% (PXG) and 86.2% (POAG). No significant inter-group differences in gender, laterality, lens status, vertical cup/disc ratio, or pre-operative best-corrected visual acuity were observed. Mean IOP comparisons showed significant differences within both groups (p<0.001). Ripcord suture removal occurred at mean 30.3±7.43 days (PXG) and 30.6±9.89 days (POAG). Median pre-operative AGM use was 4 (PXG) and 3 (POAG). No significant differences were noted postoperatively. Conclusion: To the best of our knowledge, this is the first study to evaluate the results of PGI in PXG and POAG, demonstrating a remarkable success rate and limited complications. Encouragingly, PXG patients with a history of unsuccessful filtration surgery demonstrated positive outcomes. The findings affirm PGI as a promising surgical intervention for PXG and POAG, exhibiting high success rates and manageable complications.

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Section: Discussionmentioning

confidence: 74%

Assessing the Efficacy of the PAUL Glaucoma Implant in Pseudoexfoliative Glaucoma

Olgun

2024

Beyoglu Eye J

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“…This was consistent with some Japanese studies showing a 2.5~4% mean CECD decrease 2 years after surgery, [ 30 , 31 ] even though these studies did not compare it with the contralateral eyes. However, other Japanese studies showed that the mean CECD decrease reached 18.0% at 2 years [ 31 ] and 10.3~30.0% at 2~5 years after Ex-PRESS implantation [ 32 ]. One of the factors influencing the reduction in CECD after Ex-PRESS surgery might be the shunt inserted position.…”

Section: Discussionmentioning

confidence: 99%

“…Previous studies reported no significantly faster loss in endothelial cell counts after Ex-PRESS implantation compared with trabeculectomy [ 14 , 17 , 29 ]. While other studies reported that corneal endothelial cell density (CECD) was significantly decreased after Ex-PRESS implantation [ 29 , 30 , 31 , 32 , 33 ]. However, these studies mainly done on the Japanese [ 28 , 29 , 30 ] and some on Korean [ 14 ], Italian [ 34 ] and American [ 18 ] populations.…”

Section: Introductionmentioning

confidence: 99%

Long-Term Changes in Corneal Endothelial Cell Density after Ex-PRESS Implantation: A Contralateral Eye Study

Ren

Wang

et al. 2022

JCM

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Our purpose is to evaluate long-term changes in corneal endothelial cells after Ex-PRESS shunt implantation for the treatment of glaucoma in Chinese patients by comparison with the contralateral eye. In this retrospective observational study, glaucoma patients with a single eye undergoing Ex-PRESS shunt implantation surgery were consecutively enrolled. For each patient, the clinical assessment, including corneal endothelial cell density (CECD) before surgery and at 6, 12 months, and at last follow-up (2.43 ± 0.63 years) after surgery was reviewed. The operated eyes were in the study group and the unoperated contralateral eyes were used as the control group to compare the CECD change. A total of 48 subjects (age, 51.02 ± 17.96 years) were included. The follow-up period was 2.08~3.17 years, with an average of 2.43 ± 0.63 years. At the last follow-up after the surgery, the CECD decrease in the operated eyes (5.0%) was similar to that in the contralateral eyes (3.2%) (p = 0.130). There were no significant differences in CECD reduction between the two groups at baseline and each postoperative follow-up (6 months, 12 months and at the last follow-up) (all p > 0.05). The average IOP reduction after the surgery was 50.8%, and the number of IOP-lowering medications was significantly reduced (p < 0.05). In addition, visual acuity showed no significant differences during follow-up (p > 0.05). In this study, we found that the CECD reduction of Ex-PRESS shunt-implanted Chinese eyes was similar to that of contralateral eyes without surgery.

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Sekundäre Offenwinkelglaukome: Pseudoexfoliationsglaukom, Pigmentglaukom und Neovaskularisationsglaukom

2022

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Ex-Press® versus Baerveldt implant surgery for primary open-angle glaucoma and pseudo-exfoliation glaucoma

Cited by 3 publications

References 17 publications

Assessing the Efficacy of the PAUL Glaucoma Implant in Pseudoexfoliative Glaucoma

Assessing the Efficacy of the PAUL Glaucoma Implant in Pseudoexfoliative Glaucoma

Long-Term Changes in Corneal Endothelial Cell Density after Ex-PRESS Implantation: A Contralateral Eye Study

Sekundäre Offenwinkelglaukome: Pseudoexfoliationsglaukom, Pigmentglaukom und Neovaskularisationsglaukom

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