EWSR1::WT1 Fusions in Neoplasms Other Than Conventional Desmoplastic Small Round Cell Tumor: Three Tumors Occurring Outside the Female Genital Tract

Warmke, Laura M.; Perret, Raul; Ledoux, Pauline; Michot, Audrey; Italiano, Antoine; Zou, Ying S.; Matoso, Andres; Argani, Pedram; Ulbright, Thomas M.; Baumhoer, Daniel; Ameline, Baptiste; Gross, John M.

doi:10.1016/j.modpat.2023.100418

Modern Pathology

2024

DOI: 10.1016/j.modpat.2023.100418

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EWSR1::WT1 Fusions in Neoplasms Other Than Conventional Desmoplastic Small Round Cell Tumor: Three Tumors Occurring Outside the Female Genital Tract

Laura M. Warmke,

Raul Perret,

Pauline Ledoux

et al.

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2024

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Cited by 4 publications

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Superficial Neurocristic EWSR1::FLI1 Fusion Tumor: A Distinctive, Clinically Indolent, S100 Protein/SOX10-Positive Neoplasm

Folpe,

Tetzlaff,

Billings

et al. 2024

Modern Pathology

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Superficial Neurocristic EWSR1::FLI1 Fusion Tumor: A Distinctive, Clinically Indolent, S100 Protein/SOX10-Positive Neoplasm

Folpe,

Tetzlaff,

Billings

et al. 2024

Modern Pathology

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Undifferentiated Round Cell Sarcoma With CRTC1::SS18 Fusion: Expanding Clinicopathologic Features of a Rare Translocation Sarcoma With Prominent Desmoplastic Stroma

Warmke,

Strike,

Fayad

et al. 2024

Modern Pathology

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EWSR1: the promiscuous king of mesenchymal neoplasia

Towery,

Papke

2024

J Clin Pathol

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EWSR1is the most commonly rearranged gene in mesenchymal neoplasia, and its myriad chimeric oncoproteins drive widely disparate neoplasms. Here, we survey selectedEWSR1rearrangements, including well-describedEWSR1fusions with CREB family members,ATF1andCREB1, as well as fusions in emerging entities such as mesenchymal neoplasms withEWSR1::PATZ1andEWSR1::NFATC2fusions. We also discuss recent data demonstrating the imperfect specificity ofEWSR1::WT1and, possibly,EWSR1::FLI1fusions.

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EWSR1::WT1 Fusions in Neoplasms Other Than Conventional Desmoplastic Small Round Cell Tumor: Three Tumors Occurring Outside the Female Genital Tract

Cited by 4 publications

References 56 publications

Superficial Neurocristic EWSR1::FLI1 Fusion Tumor: A Distinctive, Clinically Indolent, S100 Protein/SOX10-Positive Neoplasm

Superficial Neurocristic EWSR1::FLI1 Fusion Tumor: A Distinctive, Clinically Indolent, S100 Protein/SOX10-Positive Neoplasm

Undifferentiated Round Cell Sarcoma With CRTC1::SS18 Fusion: Expanding Clinicopathologic Features of a Rare Translocation Sarcoma With Prominent Desmoplastic Stroma

EWSR1: the promiscuous king of mesenchymal neoplasia

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