Ewing's Sarcoma of the maxillofacial region: A case report

Ewing’s Sarcoma of the Zygoma: A Very Rare Location

“…In our review, two patients underwent surgery followed by adjuvant chemotherapy, three underwent neoadjuvant chemotherapy followed by surgery, one underwent surgery followed by radiotherapy and chemotherapy, one underwent chemotherapy and radiotherapy, and one underwent surgery only [1][2][3][4][5][6][7][8][9]. We report a case in which the patient received neoadjuvant chemotherapy, and the tumor progressed during treatment, which could suggest some chemotherapy resistance.…”

“…James Ewing described Ewing´s sarcoma for the first time in 1921 [ 1 , 4 ]. It is uncommon for this type of tumor to affect the facial bones [ 3 ]. Zygoma involvement is even rarer with only a few cases reported in the English literature.…”

“…However, it is important to include this condition in the differential diagnosis for facial neoplasms with bone destruction [ 1 ]. The most common manifestation of the disease is the appearance of a mass [ 1 , 3 ]. The associated signs and symptoms are usually pain and inflammation with potential orbital involvement [ 1 ].…”

“…Some authors have argued that maxillofacial lesions have a better prognosis than lesions in other locations. This is because local signs, such as swelling, are more visible [ 2 , 3 , 9 ]. Although the treatment is well-defined in other locations, the best treatment sequence for maxillofacial tumors remains controversial.…”

“…Ewing’s sarcoma is a highly malignant neoplasm that typically affects the long bones [ 1 , 2 ]. The presence of a tumor in the facial bones occurs in only 1-4% of cases [ 3 ]. Zygoma infections are even rarer, with only a few cases reported in the literature.…”