Evolving Trend of Patients With Sars-Cov-2 in West Bengal, India.

Abstract

Objectives: COVID-19 has resulted in thousands of death worldwide and its transmission among humans is an important topic in this pandemic situation. Our study is the first comprehensive study on the evolving epidemiological trend of SARS-CoV-2 disease from patient of West Bengal, India. Study Design: Prospective observational data based study over a three-month period amongst all ages and genders. Methods: Using the gold standard Real Time PCR method to analyze nasopharyngeal and oropharyngeals swab samples for detection of RNA of SARS- CoV-2. Epidemiological data examined to detect prevalence of this disease among symptomatic to asymptomatic population. Results: Demographic data analysis showed that male population (69.79%) were more infected than female population (30.12%) by SARS-CoV-2. It was also revealed that majority positive cases under the age of 45 years were asymptomatic (64.34%) whereas symptomatic cases were more (65.75%) in older age groups. Month wise distribution amongst the positive individuals indicated that in the month of April, more positive cases (81%) were with symptoms whereas in the month of June, asymptomatic groups predominate (77%). Conclusions: The evolving trend of COVID-19 disease showing gradual shift of greater positivity among symptomatic to asymptomatic with progress of time from March to end June. It was also identified that predominantly asymptomatic presentation in the younger age group as compared to predominantly symptomatic presentation in older age group. This is expected to have public health impact in understanding the disease so that appropriate public health measures can be undertaken.

Performance of Rapid Antigen Test in Comparison to Real-Time Rt-PCR in Diagnosis of Covid-19 Infection: A Short Study

“…Similar to previous outbreaks of two beta coronaviruses, SARS-CoV in 2003 and Middle East respiratory syndrome coronavirus in 2012, were fatal in nature and have caused more than 10,000 deaths in the past two decades. SARS-CoV-2-infected disease named as coronavirus disease 2019 (COVID-19), its outbreak developing into an epidemic that quickly spread all over China and to all over the world [2,3]. Most COVID-19 virus-infected individuals will experience a mild-tosevere respiratory infection and recover without the need for special care.…”