Evolving Treatment Modality of Hand Enchondroma in a Local Hospital: From Autograft to Artificial Bone Substitutes

Tsz-Yeung, Kwok; Wong, Hin-Keung

doi:10.1016/j.jotr.2015.03.003

Cited by 5 publications

(2 citation statements)

References 9 publications

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“…In our study, graft consolidation was detected in all patients during control radiography in the sixth week. In the literature, it was reported that incorporation developed within a similar period among patients with autografts [24][25]. Our study demonstrated that usually good or excellent functional and radiologic results were obtained from curettage and autologous bone grafting with a histological diagnosis of enchondroma.…”

Section: Discussionsupporting

confidence: 65%

Surgical Treatment of Solitary Enchondromas of the Hand

Çapkın¹,

Cavit²,

Yılmaz³

et al. 2020

Cureus

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Objective: The present retrospective study evaluated the clinical and radiologic results of patients who underwent complete curettage and autologous bone grafting for hand-located isolated enchondromas with a minimum follow-up period of one year. Patients and Methods: Thirty-two patients with a follow-up period of at least 12 months who underwent operation between August 2010 and October 2018 due to the presence of solitary enchondroma of the hand were included in the study. All patients underwent complete curettage and filling of the defect via autologous bone grafting. Autologous bone graft was harvested from the iliac crest and distal radius in 24 and eight patients, respectively. The patients underwent radiography on the first postoperative visit and at six weeks, 12 weeks, and annually. The range of movement of the finger joint was evaluated by comparing it with the healthy contralateral side. Functional outcomes and radiologic outcomes were evaluated. The frequency of complications and recurrences were established. Results: Twelve patients were male and 20 were female. The average age was 34 (range: 16-56) years. The most common digit involved was the little finger (nine cases, 28.125%); the proximal phalanx was the most common location (17 cases, 53.125%). Control radiography in the sixth week revealed graft consolidation in all patients. No case of nonunion or recurrence was detected clinically or radiologically, with a mean follow-up period of 54 (range: 12-96) months. Functional outcomes were classified as excellent in 28 patients and as good in four patients. The final radiographic appearances included Tordai's group 1 in 28 bones and group 2 in four bones. Conclusion: Curettage and autologous bone grafting are safe, costless, and effective treatment options for hand enchondroma, with satisfactory functional and radiographic outcomes. Harvesting bone graft from the distal radius provides a shorter length of hospital stay and lower complication rates compared to obtaining the graft from the iliac crest.

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Section: Discussionsupporting

confidence: 65%

Surgical Treatment of Solitary Enchondromas of the Hand

Çapkın¹,

Cavit²,

Yılmaz³

et al. 2020

Cureus

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“…DBX was used as a graft in the treatment of enchondromas of the hand. Kwon and Wong, 34 and Dietz, Kachar and Nagle, 33 reported small case series of five and two patients, respectively. No recurrence or pathological fractures were reported.…”

Section: Resultsmentioning

confidence: 99%

The available evidence on demineralised bone matrix in trauma and orthopaedic surgery

Stok

Hartholt

Schoenmakers

et al. 2017

Bone & Joint Research

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ObjectivesThe aim of this systematic literature review was to assess the clinical level of evidence of commercially available demineralised bone matrix (DBM) products for their use in trauma and orthopaedic related surgery.MethodsA total of 17 DBM products were used as search terms in two available databases: Embase and PubMed according to the Preferred Reporting Items for Systematic Reviews and Meta Analyses statement. All articles that reported the clinical use of a DBM-product in trauma and orthopaedic related surgery were included.ResultsThe literature search resulted in 823 manuscripts of which 64 manuscripts met the final inclusion criteria. The included manuscripts consisted of four randomised controlled trials (level I), eight cohort studies (level III) and 49 case-series (level IV). No clinical studies were found for ten DBM products, and most DBM products were only used in combination with other grafting materials. DBM products were most extensively investigated in spinal surgery, showing limited level I evidence that supports the use Grafton DBM (Osteotech, Eatontown, New Jersey) as a bone graft extender in posterolateral lumbar fusion surgery. DBM products are not thoroughly investigated in trauma surgery, showing mainly level IV evidence that supports the use of Allomatrix (Wright Medical, London, United Kingdom), DBX (DePuy Synthes, Zuchwil, Switzerland), Grafton DBM, or OrthoBlast (Citagenix Laval, Canada) as bone graft extenders.ConclusionsThe clinical level of evidence that supports the use of DBM in trauma and orthopaedic surgery is limited and consists mainly of poor quality and retrospective case-series. More prospective, randomised controlled trials are needed to understand the clinical effect and impact of DBM in trauma and orthopaedic surgery.Cite this article: J. van der Stok, K. A. Hartholt, D. A. L. Schoenmakers, J. J. C. Arts. The available evidence on demineralised bone matrix in trauma and orthopaedic surgery: A systemati c review. Bone Joint Res 2017;6:423–432. DOI: 10.1302/2046-3758.67.BJR-2017-0027.R1.

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