Evolving role of nuclear medicine for the diagnosis and management of urinary tract infection

Jj, Conway; Ra, Cohn

doi:10.1016/s0022-3476(94)70258-6

Cited by 37 publications

(2 citation statements)

References 28 publications

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“…Consequently, DMSA renal scintigraphy provides a unique opportunity to study the progression of renal damage and functional loss from the initial insult of APN to the subsequent development of irreversible renal scarring 52 . Accordingly, DMSA renal scanning is currently the “gold standard” for identifying renal parenchymal changes, including scarring 52, 54, 61, 62 . As such, DMSA renal scans will be used in the NIH RIVUR study as the outcome measurement for the detection and semi-quantification of both pre-existent and newly acquired renal parenchymal damage secondary to UTIs in children with grades I–IV VUR.…”

Section: F Background To Imaging Studiesmentioning

confidence: 99%

Randomized Intervention for Children With Vesicoureteral Reflux (RIVUR): Background Commentary of RIVUR Investigators

et al. 2008

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Because of the frequency of urinary tract infections in children, off-label use of antimicrobial prophylaxis is often the usual treatment of children with vesicoureteral reflux, and such use is increasingly being called into question; hence, a definitive study to determine the value of antimicrobial prophylaxis with regard to the recurrence of urinary tract infection and the incidence of renal scarring is essential. The currently recommended follow-up procedures (repeated urine cultures, renal and genitourinary imaging, antimicrobial therapy and prophylaxis, as well as other factors including cleanliness, adequate bladder and bowel emptying, and compliance with protocols) are expensive (in terms of time, attention to detail, and cost) and cumbersome. Such recommendations should be evidence-based.

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Section: F Background To Imaging Studiesmentioning

confidence: 99%

Randomized Intervention for Children With Vesicoureteral Reflux (RIVUR): Background Commentary of RIVUR Investigators

et al. 2008

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“…7 Approximately 13% to 15% of end -stage renal disease is thought to be related to urinary tract infection in childhood that was often unrecognized and therefore, under treated. 8 The present study is undertaken to estimate the prevalence of urinary tract infection in febrile children less than 5 years of age and to assess the validity of routine microscopic urine analysis and urine culture in the diagnosis of Urinary Tract infection.…”

Section: Introductionmentioning

confidence: 99%

Prevalence of urinary tract infection in febrile children of less than five years of age

Mahishma¹,

K²

2021

IJMPO

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To determine the prevalence of urinary tract infection in febrile children, less than 5 years of age. To assess the validity of microscopic urine analysis and urine culture in the diagnosis of urinary tract infection.Prospective study. Children attending the department of paediatrics, Dr.V.R.K. Women’s Medical College, Teaching Hospital & Research Centre, with febrile illness during June 2019-June 2020.370 children between 1 month to 5 years of age.Data related to age, sex, nutritional status, socioeconomic status and predisposing risk factors like urethral instrumentation, bowel habits etc, were noted. A thorough physical examination with relevant investigations were carried out in all these patients. Routine urinary microscopy was done in all patients and urine culture was done in those who showed pyuria of >5 pus cells/HPF in centrifuged urine sample.In our study, overall prevalence of UTI was 3.5% in children between 1 month to 5 yrs and 4.1% in children <2yrs and 7% in Children <1 year of age with M:F ratio of 1:1in children <2yrs. Prevalence of culture positivity was 44% in those who showed >10 pus cells/HPF in centrifuged sample of urine and 2.5% in those who showed >5pus cells/HPF.The presence of obvious source of fever such as upper respiratory tract infection or otitis media is not reliable in excluding urinary tract infection. Overall prevalence of UTI in our study was low (3.5%) and prevalence among children <2yrs was 4.1% and <1 year of age was 7%. Pyuria of >5pus cells/HPF (centrifuged urine sample) should be considered as significant and further evaluation should be done to initiate prompt treatment.

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Urinary Tract Infections

Bailey¹

2003

Family Medicine

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Evolving role of nuclear medicine for the diagnosis and management of urinary tract infection

Cited by 37 publications

References 28 publications

Randomized Intervention for Children With Vesicoureteral Reflux (RIVUR): Background Commentary of RIVUR Investigators

Randomized Intervention for Children With Vesicoureteral Reflux (RIVUR): Background Commentary of RIVUR Investigators

Prevalence of urinary tract infection in febrile children of less than five years of age

Urinary Tract Infections

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